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Table 4 Multivariable Cox proportional hazard model for OS in unmatched cohort

From: Video-assisted thoracoscopic lobectomy versus open lobectomy in the treatment of large lung cancer: propensity-score matched analysis

Variable

Univariable analysis

Multivariable analysis

Hazard ratio

95% CI

P value

Hazard ratio

95% CI

P value

VATS (vs. thoracotomy)

0.56

0.38

0.82

0.003

0.81

0.54

1.23

0.331

Sex, male (vs. female)

2.23

1.28

3.88

0.005

1.65

0.93

2.95

0.087

Age (per year)

1.05

1.03

1.08

 < 0.001

1.04

1.02

1.07

 < 0.001

CCI ≥ 2 (vs. CCI < 2)

2.10

1.34

3.30

0.001

1.72

1.09

2.74

0.021

FEV1 ≥ 80% (vs. < 80%)

1.02

0.66

1.56

0.935

    

DLCO ≥ 80% (vs. < 80%)

0.77

0.45

1.32

0.349

    

Pathologic tumor size

1.02

1.01

1.03

 < 0.001

1.02

1.01

1.03

 < 0.001

Pathologic N + (vs. pN0)

1.90

1.32

2.75

0.001

2.33

1.60

3.40

 < 0.001

Histology (ref = ADC)

   

0.009

    

SCC

1.65

1.16

2.36

 

1.13

0.77

1.65

0.542

Others

0.87

0.46

1.66

 

0.86

0.44

1.65

0.643

Adjuvant treatment

0.65

0.47

0.92

0.013

0.69

0.47

1.03

0.071

  1. Statistically significant variates (P < 0.1) in the univariable analysis were used as covariates for multivariable analysis
  2. VATS video-assisted thoracic surgery, CCI Charlson comorbidity index, FEV1 forced expiratory volume at 1 s, DLCO diffusing capacity for carbon monoxide, ADC adenocarcinoma, SCC squamous cell carcinoma
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Journal of Cardiothoracic Surgery

ISSN: 1749-8090

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