The effect of first- and third-generation prophylactic antibiotics on hospitalization and medical expenditures for cardiac surgery

Table 2 Clinical outcomes of patients receiving 1st generation prophylactic antibiotics compared to 3rd generation

	3rd generation (n = 194)	1st generation (n = 194)	Crude OR (95% CI)	Adjusted OR (95% CI)
All surgical site infections	52 (26.8)	30 (15.4)	1.19 (1.01–1.71)	1.10 (1.01–1.62)*
Superficial surgical site infection	20 (10.3)	19 (9.8)	0.91 (0.71–1.30)	0.87 (0.62–1.11)
Deep SSI/mediastinitis	32 (16.5)	11 (5.7)	1.36 (1.11–2.08)	1.25 (1.07–1.91)**

Values are presented as the number (%). *p < 0.05, **p < 0.001
Adjustment variables: age, sex, DM, obesity, smoking, emergency, internal thoracic artery (ITA) harvested, ventilator time, duration of ICU stay, and enrollment period

ISSN: 1749-8090