Table 5 Subgroup analysis assessing large volume transfusion (> 4 units PRBC)
Factor | Odds ratio (95% CI) | P value | Adjusted odds ratio | P value |
|---|---|---|---|---|
Gender (female vs. male) | 0.993 (0655–1.506) | P = 0.974 |  |  |
Age (per year increase) | Â | Â | Â | Â |
Creatinine (per µmol/L increase) | 1.003 (1.002–1.004) | P = 0.001 | 1.007 (1.004–1.010) | P < 0.001 |
Respiratory disease ( yes vs. no ) | 2.049 (1.335–3.146) | P = 0.001 | 1.872 (1.170–3.000) | P = 0.009 |
Dialysis (yes vs. no ) | 4.103 (1.809–9.306) | P < 0.001 | 30.24 (2.549–358.7) | P = 0.007 |
Smoking (yes vs. no) | 0.937 (0.637–1.378) | P = 0.741 |  |  |
BMI (per kg/m2 increase) | 0.956 (0.922–0.991) | P = 0.019 | 0.950 (0.914–0.987) | P = 0.008 |
TBSA (per m2 increase) | 0.706 (0.304–1.637) | P = 0.417 |  |  |
NYHA class 4 | 1.194 (0.780–1.829) | P = 0.872 |  |  |
Preoperative Hb (per g/L increase) | 0.967 (0.957–0.976) | P < 0.001 | 0.971 (0.961–0.982) | P < 0.001 |
Antiplatelet use < 24 h ( yes vs. no ) | 1.063 (0.504–2.246) | P = 0.872 |  |  |
Anticoagulant use < 24 h ( yes vs. no ) | 1.194 (0.780–1.829) | P = 0.414 |  |  |
Non valve/CABG ( yes vs. no ) | 1.259 (0.754–2.102) | P = 0.378 |  |  |
Previous cardiothoracic intervention ( yes vs. no ) | 2.877 (1.934–4.281) | P < 0.001 | 2.578 (1.681–3.953) | P < 0.001 |
Presence of cardiogenic shock preoperatively (yes vs. no) | 7.260 (4.480–11.77) | P < 0.001 | 6.329 (3.788–10.53) | P < 0.001 |