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Table 5 Subgroup analysis assessing large volume transfusion (> 4 units PRBC)

From: Preoperative patient factors associated with blood product use in cardiac surgery, a retrospective cohort study

Factor Odds ratio (95% CI) P value Adjusted odds ratio P value
Gender (female vs. male) 0.993 (0655–1.506) P = 0.974   
Age (per year increase)     
Creatinine (per µmol/L increase) 1.003 (1.002–1.004) P = 0.001 1.007 (1.004–1.010) P < 0.001
Respiratory disease ( yes vs. no ) 2.049 (1.335–3.146) P = 0.001 1.872 (1.170–3.000) P = 0.009
Dialysis (yes vs. no ) 4.103 (1.809–9.306) P < 0.001 30.24 (2.549–358.7) P = 0.007
Smoking (yes vs. no) 0.937 (0.637–1.378) P = 0.741   
BMI (per kg/m2 increase) 0.956 (0.922–0.991) P = 0.019 0.950 (0.914–0.987) P = 0.008
TBSA (per m2 increase) 0.706 (0.304–1.637) P = 0.417   
NYHA class 4 1.194 (0.780–1.829) P = 0.872   
Preoperative Hb (per g/L increase) 0.967 (0.957–0.976) P < 0.001 0.971 (0.961–0.982) P < 0.001
Antiplatelet use < 24 h ( yes vs. no ) 1.063 (0.504–2.246) P = 0.872   
Anticoagulant use < 24 h ( yes vs. no ) 1.194 (0.780–1.829) P = 0.414   
Non valve/CABG ( yes vs. no ) 1.259 (0.754–2.102) P = 0.378   
Previous cardiothoracic intervention ( yes vs. no ) 2.877 (1.934–4.281) P < 0.001 2.578 (1.681–3.953) P < 0.001
Presence of cardiogenic shock preoperatively (yes vs. no) 7.260 (4.480–11.77) P < 0.001 6.329 (3.788–10.53) P < 0.001