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Table 1 Profound features of three generations of drug eluting stent

From: Evolutionary perspective of drug eluting stents: from thick polymer to polymer free approach

Generations

Platform

Strut thickness

Polymer

Polymer type

Drugs

Commercially available DES

1st

Stainless Steel

 > 130

SIBS

PEVA

PBMA

Permanent

Sirolimus

Paclitaxel

Cypher

Taxus

2nd

CoCr

PtCr

80 µm to 100 µm

PVDF-HFP

BioLinks

Permanent

Everolimus

Zotrolimus

Xience

Endeavour

Resolute

3rd

A

CoCr

PtCr

55 µm to 85 µm

PLA

PGLA

Biodegradable

Sirolimus

Everolimus

Biolimus

YukonPC

Biomatrix

Orsiro

Ultimaster

Synergy

B

CoCr

Stainless steel

70 µm to 90 µm

Polymer free

–

Sirolimus

Probucol

YukonChrome

ISAR

4th

PLLA

Magnesium

130–150

PLLA

PDLLA

Biodegradable

Sirolimus

Novolimus

Everolimus

Absorb

Absorb-GT1

MeRes

Magmaris