From: Evolutionary perspective of drug eluting stents: from thick polymer to polymer free approach
Generations | Platform | Strut thickness | Polymer | Polymer type | Drugs | Commercially available DES | |
---|---|---|---|---|---|---|---|
1st | Stainless Steel |  > 130 | SIBS PEVA PBMA | Permanent | Sirolimus Paclitaxel | Cypher Taxus | |
2nd | CoCr PtCr | 80 µm to 100 µm | PVDF-HFP BioLinks | Permanent | Everolimus Zotrolimus | Xience Endeavour Resolute | |
3rd | A | CoCr PtCr | 55 µm to 85 µm | PLA PGLA | Biodegradable | Sirolimus Everolimus Biolimus | YukonPC Biomatrix Orsiro Ultimaster Synergy |
B | CoCr Stainless steel | 70 µm to 90 µm | Polymer free | – | Sirolimus Probucol | YukonChrome ISAR | |
4th | PLLA Magnesium | 130–150 | PLLA PDLLA | Biodegradable | Sirolimus Novolimus Everolimus | Absorb Absorb-GT1 MeRes Magmaris |