Variable | First tertile (n = 53) | Second tertile (n = 53) | Third tertile (n = 53) | P |
---|---|---|---|---|
Demographic characteristics | Â | Â | Â | Â |
Age, years | 55.0 ± 12.0 | 53.5 ± 12.0 | 50.4 ± 11.6 | 0.136 |
Male, n (%) | 41 (77.4) | 35 (66.0) | 42 (79.2) | 0.243 |
BMI, kg/m2 | 25.2 (23.5, 27.4) | 25.3 (22.4, 28.1) | 24.9 (22.3, 28.7) | 0.951 |
Past medical history, n (%) | Â | Â | Â | Â |
Hypertension | 50 (94.3) | 49(92.5) | 48(90.6) | 0.763 |
Diabetes mellitus | 1 (1.9) | 2 (3.8) | 2 (3.8) | 0.813 |
Atrial fibrillation | 1 (1.9) | 1 (1.9) | 1 (1.9) | 0.999 |
Current smoking | 25 (47.2) | 25 (47.2) | 28 (52.8) | 0.797 |
Coronary heart disease | 4 (7.5) | 3 (5.7) | 1 (1.9) | 0.398 |
Clinical assessment | Â | Â | Â | Â |
APACHE II, score | 12 (10, 15) | 12 (10, 14) | 12 (10, 15) | 0.566 |
EuroSCORE, score | 5 (5, 6) | 5 (5, 6) | 5 (4, 6) | 0.610 |
Systolic blood pressure, mmHg | 142 (128, 164) | 136 (125, 158) | 140 (126, 158) | 0.569 |
Diastolic blood pressure, mmHg | 81 (70, 97) | 71 (64, 88) | 74 (67, 89) | 0.060 |
HR, /min | 78 (66, 87) | 78 (70, 87) | 80 (70, 87) | 0.830 |
Total arch replacement, n (%) | 38 (71.7) | 43 (81.1) | 46 (86.8) | 0.147 |
Semi-arch replacement, n (%) | 12 (22.6) | 6 (11.3) | 5 (9.4) | 0.112 |
Stented elephant trunk, n (%) | 42 (79.2) | 42 (79.2) | 47 (88.7) | 0.338 |
Bentall procedure, n (%) | 6 (11.3) | 2 (3.8) | 1 (1.9) | 0.084 |
Ascending aorta replacement, n (%) | 49 (92.5) | 51 (96.2) | 52 (98.1) | 0.351 |
Blood transfusion, ml | 3475 (2890, 4350) | 2980 (2360, 3560) | 3560 (2725, 4250) | 0.021 |
CPB time, min | 172 (153, 179) | 160 (135, 170) | 174 (149, 186) | 0.023 |
Cross-clamp time, min | 96 (80, 107) | 85 (69, 96) | 95 (80, 112) | 0.004 |
DHCA time, min | 20 (18, 21) | 19 (17, 20) | 20 (19, 22) | 0.001 |
AKI, n (%) | 27 (50.9) | 13 (24.5) | 7 (13.2) | 0.001 |
Baseline laboratory data | Â | Â | Â | Â |
Scr, umol/L | 87.4 (69.4, 109.2) | 71.1 (54.9, 94.2) | 71.7 (60.7, 95.2) | 0.009 |
TC, mmol/L | 2.64 (2.24, 3.00) | 2.85 (2.41, 3.43) | 2.40 (1.92, 3.15) | 0.021 |
TG, mmol/L | 1.26 (0.93, 1.55) | 1.16 (0.89, 1.76) | 1.37 (0.95, 2.10) | 0.507 |
HDL, mmol/L | 0.74 ± 0.19 | 0.73 ± 0.23 | 0.76 ± 0.19 | 0.090 |
LDL, mmol/L | 1.27 (0.97, 1.55) | 1.44 (1.07, 1.78) | 1.07 (0.87, 1.56) | 0.025 |
Blood glucose, mmol/L | 7.06 (6.27, 8.04) | 6.85 (6.13, 8.25) | 7.54 (6.43, 8.61) | 0.274 |
Lac, mmol/L | 1.40 (0.90, 1.90) | 1.00 (0.80, 1.80) | 1.20 (0.80, 2.50) | 0.589 |