Table 4 Results of this meta-analysis and the subgroup analyses
From: Predictive model for the probability of malignancy in solitary pulmonary nodules: a meta-analysis
Studies (n) | Sensitivity (95% CI) | Specificity (95% CI) | PLR (95% CI) | NLR (95% CI) | |
|---|---|---|---|---|---|
All studies | 20 | 88% (84–91%) | 78% (74–80%) | 3.91 (3.42–4.46) | 0.16 (0.12–0.21) |
Reference standard | |||||
Surgery only | 10 | 84% (77–89%) | 77% (71–81%) | 3.56 (2.92–4.36) | 0.22 (0.15–0.30) |
Surgery and biopsy | 10 | 91% (87–93%) | 79% (75–82%) | 4.29 (3.59–5.14) | 0.12 (0.09–0.16) |
Blind | |||||
Yes | 5 | 86% (81–90%) | 73% (67–78%) | 3.14 (2.56–3.85) | 0.19 (0.14–0.26) |
Unclear | 15 | 88% (83–92%) | 80% (76–83%) | 4.33 (3.73–5.02) | 0.15 (0.10–0.21) |