Table 1 Basic characteristics of included studies
From: Review of outcomes of delayed chest closure following lung transplantation: a meta-analysis
Authors, year | Design | Country | Enrolled year | Quality | NOS | DCC/PCC cohorts, n | Bilateral lung Tx, DCC/PCC, n (%) | Indications for transplantation, n (%) | Type of incision | Indications for DCC, n (%) | Duration of DCC (days, median [range]) |
|---|---|---|---|---|---|---|---|---|---|---|---|
Force [6] | Single-center, retrospective | The United States | 2003–2005 | Good | 7 | 7/21 | 7(100)/21(100) | DCC: COPD/A1AT, 1(14); CF, 1(14); IPF, 1(14); Sarcoidosis/PH, 3(43); Eisenmenger’s Syndrome, 1(14); PCC: COPD/A1AT, 13(62); CF/ bronchiectasis, 4(19); IPF, 4(19) | Bilateral anterior thoracotomy with or without sternal divisiona | based on cardiac and pulmonary impairment during attempted closurea | 5.3 [3–7] |
Shigemura [4] | Single-center, retrospective | The United States | 2004–2011 | Good | 8 | 90/783 | 90(100)/75(10) | DCC: COPD, 8(9); IPF, 37(41); PPH, 20(22); scleroderma, 15(16); other, 11(12); PCC: COPD, 282(36); IPF, 149(19); PPH, 78(10); scleroderma, 47(6); other, 227(29) | NR | Acute lung edema, 40(44); oversized allografts, 38(42); coagulopathy, 29(32); hemodynamic instability, 18(20) | 4.5(mean) [1–18] |
Aguila [2] | Single-center, retrospective | The United States | 2010–1014 | Good | 8 | 67/165 | 66(99)/161(98) | DCC: COPD, 3(4); ILD, 45(67); CF, 8(12); PH, 3(4); re-transplantation, 4(6); other, 4(6); PCC: COPD, 59(36); ILD, 59(36); CF, 33(20); PH, 4(2); re-transplantation, 4(2); other, 6(4) | bilateral, standard anterior thoracotomy; single, posterolateral thoracotomya | Acute lung edema, oversized allografts, coagulopathy, hemodynamic instabilitya | 2 |
Rafiroiu [5] | Single-center, retrospective | The United States | 2009–2016 | Good | 7 | 46/46 | 44(96)/43(93) | DCC: IPF, 20(43); CF, 4(9); re-transplantation, 3(7); other, 19(41); PCC: IPF, 17(37); CF, 9(20); re-transplantation, 3(7); other, 17(37) | DCC: thoracotomy, 1(2); sternotomy, 32(70); clamshell, 13(28); PCC: thoracotomy, 6(13); sternotomy, 25(54); clamshell, 15(33) | Coagulopathy/bleeding, hemodynamic instability, hypoxiaa | 3 [2–6.2] |