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Table 3 Operation characteristics between the male and female patients in tranexamic acid before and after propensity score matching

From: Impact of gender differences on hemostasis in patients after coronary artery bypass grafts surgeries in the context of tranexamic acid administration

Surgery data

Before matching

After matching

Female (n = 6905)

Male (n = 22,631)

p-value

Female (n = 6808)

Male (n = 6808)

p-value

CABGs by experienced surgeons (≥ 100 CABGs / year), n (%)

3692(53.5)

12,186(53.8)

0.581

3628(53.3)

3641(53.5)

0.838

Operation year (2009–2014), n (%)

2561(37.1)

8437(37.3)

0.773

2509(36.9)

2452(36.0)

0.319

Operation year (2015–2019), n (%)

4344(62.9)

14,194(62.7)

0.773

4299(63.1)

4356(64.0)

0.319

High risk operation, n (%)

1420(20.6)

4190(18.5)

 < 0.0001

1397(20.5)

1408(20.7)

0.832

Emergent surgery, n (%)

233(3.4)

647(2.9)

0.027

226(3.3)

212(3.1)

0.529

Elective, n (%)

6672(96.6)

21,984(97.1)

0.027

6582(96.7)

6596(96.9)

0.529

Isolated CABG, n (%)

5710(82.7)

19,110(84.4)

0.001

5632(82.7)

5612(82.4)

0.667

On-pump, n (%)

4365(63.2)

14,202(62.8)

0.488

4312(63.3)

4328(63.6)

0.790

Open-chamber, n (%)

1172(17.0)

3411(15.1)

 < 0.0001

1153(16.9)

1172(17.2)

0.681

Heparin neutralization ratio, mean ± SD

1.41 ± 0.50

1.33 ± 0.46

 < 0.0001

1.40 ± 0.50

1.40 ± 0.48

0.766

Duration of surgery (min), mean ± SD

286.36 ± 84.72

293.40 ± 85.88

 < 0.0001

286.48 ± 84.65

290.43 ± 87.38

0.007

  1. High risk: previous cardiac surgery, emergent surgery, CABG combined with valve operation and CABG combined with aortic or arch operation; Open chamber: CABG combined with valve surgery or aortic surgery or aneurysm resection; SD, standardized deviation. High risks operation: previous cardiac surgery, emergent surgery, CABG combined with valve operation or CABG combined with aortic or arch operation
  2. CABG coronary artery bypass graft