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Table 1 Basic characteristics of the included studies

From: Effect of catheter ablation combined with left appendage occlusion for non-valvular atrial fibrillation: a meta-analysis

Study/year Sample size Gender (male/female) Age Country Follow-up (month) TEE follow-up (month) CHADS2 CHA2DS2-VASc HAS-BLED MINORS
Swaans 2012 [14] 30 21/9 62.8 ± 8.5 Netherlands 12 6 2.5 3 2 19
Walker 2012 [15] 26 20/6 63.0 ± 7.0 Australia 12 6 1.9 2.6 - 17
Swaans 2013 [16] 10 5/5 61.6 ± 9.6 Netherlands 6 1.5 3 3.5 1.5 13
Alipour 2015 [8] 62 40/22 64.0 ± 8.0 Netherlands 38 2 2.5 3.0 2 17
Calvo 2015 [7] 35 25/10 70.0 ± 7.0 Spain 13 3 2.01 3.1 3.1 16
Romanov 2015 [17] 45 28/17 60.0 ± 5.0 Russia 24 6 - 2.2 3.5 14
Phillips 2016 [9] 98 67/31 65.0 ± 7.0 Austrialia 26.73 12 1.5 2.6 1.9 15
Fassini 2016 [10] 35 28/35 72.0 ± 4.0 Italy 24 12 - 3 3 15
Panikker 2016 [18] 20 13/7 68.0 ± 7.0 United Kindom 12 9 - 3.1 2.5 16
Pelissero 2017 [19] 21 14/7 68.42 ± 10.61 Italy 14.93 14.93 - 2.8 3.2 15
Wintgens 2018 [13] 349 202/147 63.1 ± 8.2 Netherlands/Russia/Australia/Spain 34.5 3 2.0 3.0 3.0 15
Phillips 2018 [20] 139 76/139 64.1 ± 7.3 Australia/Russia/Netherlands/Italy/USA/Malaysia 1 1 2.2 3.4 1.5 17
Du 2018 [21] 82 48/34 66.2 ± 8.4 China 11.2 6 - 4.4 3.5 18
Li 2020 [22] 61 25/36 66.7 ± 9.2 China 24 12 - 4.2 3.4 19
Ren 2020 [23] 76 47/29 67.0 ± 7.5 China 24 12 - 3.4 2.3 16
Mo 2020 [24] 76 39/37 69.9 ± 7.9 China 24 6 - 3.6 3.3 18
Chen 2020 [25] 178 94/84 68.9 ± 8.1 China 12 3 - 3.3 1.6 17
Ren 2020 [26] 42 26/16 70.0 ± 7.6 China 20 12 - 3.8 3.7 17
  1. TEE, transesophageal echocardiography. MINORS, methodological index for non-randomized studies