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Table 1 Case series summary of surgical treatment of TAAAD complicated with CM

From: Surgical treatment of type A acute aortic dissection with cerebral malperfusion: a systematic review

Author Article types Year N of patients Incidence (%) Age (years) Sex (F) In-hospital mortality (%) Causes of death Follow-up (mo)
Okita et al. [12] RS 2021 50 13.1 68.1 ± 9.2 NA 14 (28%) Stroke 8 5-year survival (75.2 ± 12.5%)
10-year survival (60.5 ± 23.4%)
Sugiyama et al. [13] RS 2021 19 21 69 (39–84) 2 2 (10.5%) Extensive cerebral infarction NA
Gomibuchi et al. [14] RS 2021 42 21.3 64.9 ± 11.1 22 2 (4.8%) NA NA
Sasaki et al. [8] RS 2020 9 7.1 66.2 ± 12.9 8 0 0 24 (all survival)
Shimura et al. [15] RS 2020 16 7.7 63 (32–83) 8 1 (6.3%) Severe cerebral edema 101 ± 7
Luehr et al. [16] RS 2016 23 6.5 66.3 (55.2–69.9) 5 3 (13.0%) Cerebral haemorrhag 2, MOF 1 15.2 (4.8–34.1)
Di Eusanio et al. [3] RS 2013 99 7.5 63.1 ± 13.7 62.8 ± 12.2 NA 33 (33.3%) NA Median 36
5-year survival: 67.1% (CVA), 57.1% (coma)
Morimoto et al. [5] RS 2011 41 26.1 67.3 ± 10.0, 69.7 ± 11.5 16 6 (14.6%) Large hemispheric infarction 57.6 (1.2–136.8)
5-year survival 65% ± 8%
10-year survival 59% ± 9%
Nakamura [17] RS 2011 10 22.4 69 ± 9 (57–84) 5 0 0 18 ± 5
Tsukube et al. [18] RS 2011 24 14.9 71.9 (44–91) 18 4 (16.7%) Aortic rupture 1, AMI 1, massive brain edema 2 34.5 ± 25.1
3 years cumulative survival rate 71.8%
Estrera et al. [9] RS 2006 14 19 56 (43–73) 6 1 (7%) Small bowel necrosis 18.5
1-year survival 81.3%
5-year survival 58.0%
Tanaka et al. [19] RS 2005 16 25.3 71.6 ± 7.7 10 7 (43.7%) Severe brain damage 25.2 ± 21 (2–56)
4-year survival 50.1%
Total RS 2005–2021 363 (15.5%) 15.9 65.7 ± 13 (32–91) 100 73 (20.1%) Neurological damage (n = 28), MOF (n = 1), aortic rupture (n = 1), AMI (n = 1), small bowel necrosis (n = 1) 40.1 ± 37.6
5 years survival 65.3 ± 11%
  1. AMI = acute myocardial infarction; CM = cerebral malperfusion; mo = month; MOF = multiorgan failure; NA = not available; TAAAD = Type A acute aortic dissection