Table 1 Baseline patient characteristics
From: Does the “obesity paradox” exist after transcatheter aortic valve implantation?
Variable | Overall (n = 109) | BMI (kg/m2) | p-value | ||
|---|---|---|---|---|---|
< 21.9 (n = 27) | 21.9–27.0 (n = 55) | > 27.0 (n = 27) | |||
Age (years) | 72.0 ± 8.8 | 71.2 ± 7.4 | 72.0 ± 7.4 | 74.8 ± 8.8 | < 0.001 |
Men | 67 (61.5%) | 18 (66.7%) | 31 (56.4%) | 18 (66.7%) | 0.543 |
Body mass index (kg/m2) | 25.0 [21.9, 27.0] | 20.3 [19.4, 21.2] | 25.0 [23.4, 25.9] | 30.3 [28.0, 34.4] | < 0.001 |
New York Heart Association class III or IV | 87 (79.8%) | 21 (77.8%) | 44 (80.0%) | 22 (81.5%) | 0.943 |
Hypertension | 94 (86.2%) | 21 (77.8%) | 48 (87.3%) | 25 (92.6%) | 0.310 |
Diabetes mellitus | 37 (33.9) | 7 (25.9%) | 15 (27.3%) | 15 (55.6%) | 0.026 |
Previous myocardial infarction | 16 (14.7%) | 5 (18.5%) | 6 (10.9%) | 5 (18.5%) | 0.593 |
Previous coronary artery bypass graft | 18 (16.5%) | 4 (14.8%) | 8 (14.5%) | 6 (22.2%) | 0.708 |
Previous percutaneous coronary intervention | 28 (25.7%) | 4 (14.8%) | 12 (21.8%) | 12 (44.4%) | 0.026 |
Previous valve surgery | 5 (4.6%) | 2 (7.4%) | 2 (3.6%) | 1 (3.7%) | 0.836 |
Peripheral artery disease | 36 (33.0%) | 8 (29.6%) | 18 (32.7%) | 10 (37.0%) | 0.834 |
Previous stroke/transient ischemic attack | 18 (16.5%) | 4 (14.8%) | 8 (14.5%) | 6 (22.2%) | 0.708 |
Chronic lung diseasea | 37 (33.9%) | 4 (14.8%) | 22 (40.0%) | 11 (40.7%) | 0.051 |
Glomerular filtration rate (mL/min/m2) | 55.9 ± 25.5 | 61.4 ± 17.0 | 55.9 ± 19.6 | 50.0 ± 15.2 | 0.024 |
Previous pacemaker | 14 (12.8%) | 3 (11.1%) | 9 (16.4%) | 2 (7.4%) | 0.570 |
Atrial fibrillation | 27 (24.8%) | 4 (14.8%) | 19 (34.5%) | 4 (14.8%) | 0.064 |
Frailtyb | 31 (28.4%) | 5 (18.5%) | 13 (23.6%) | 13 (48.1%) | 0.032 |
Ejection fraction (%) | 56.8 ± 14.9 | 56.0 ± 14.9 | 58.0 ± 13.2 | 56.3 ± 10.4 | 0.250 |
Aortic valve area (cm2) | 0.63 ± 0.16 | 0.63 ± 0.15 | 0.63 ± 0.16 | 0.64 ± 0.15 | 0.998 |
Aortic valve mean gradient (mm Hg) | 45.4 ± 13.6 | 46.0 ± 13.3 | 44.9 ± 14.2 | 45.4 ± 13.0 | 0.386 |
Aortic valve maximal gradient (mm Hg) | 76.2 ± 21.4 | 77.1 ± 20.8 | 74.2 ± 22.2 | 77.0 ± 20.5 | 0.286 |
CT mean annulus diameter (mm) | 24.3 ± 2.7 | 24.3 ± 2.8 | 24.4 ± 2.5 | 24.2 ± 2.5 | 0.980 |