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Table 1 Baseline patient characteristics

From: Does the “obesity paradox” exist after transcatheter aortic valve implantation?

Variable Overall (n = 109) BMI (kg/m2) p-value
 < 21.9 (n = 27) 21.9–27.0 (n = 55)  > 27.0 (n = 27)
Age (years) 72.0 ± 8.8 71.2 ± 7.4 72.0 ± 7.4 74.8 ± 8.8  < 0.001
Men 67 (61.5%) 18 (66.7%) 31 (56.4%) 18 (66.7%) 0.543
Body mass index (kg/m2) 25.0 [21.9, 27.0] 20.3 [19.4, 21.2] 25.0 [23.4, 25.9] 30.3 [28.0, 34.4]  < 0.001
New York Heart Association class III or IV 87 (79.8%) 21 (77.8%) 44 (80.0%) 22 (81.5%) 0.943
Hypertension 94 (86.2%) 21 (77.8%) 48 (87.3%) 25 (92.6%) 0.310
Diabetes mellitus 37 (33.9) 7 (25.9%) 15 (27.3%) 15 (55.6%) 0.026
Previous myocardial infarction 16 (14.7%) 5 (18.5%) 6 (10.9%) 5 (18.5%) 0.593
Previous coronary artery bypass graft 18 (16.5%) 4 (14.8%) 8 (14.5%) 6 (22.2%) 0.708
Previous percutaneous coronary intervention 28 (25.7%) 4 (14.8%) 12 (21.8%) 12 (44.4%) 0.026
Previous valve surgery 5 (4.6%) 2 (7.4%) 2 (3.6%) 1 (3.7%) 0.836
Peripheral artery disease 36 (33.0%) 8 (29.6%) 18 (32.7%) 10 (37.0%) 0.834
Previous stroke/transient ischemic attack 18 (16.5%) 4 (14.8%) 8 (14.5%) 6 (22.2%) 0.708
Chronic lung diseasea 37 (33.9%) 4 (14.8%) 22 (40.0%) 11 (40.7%) 0.051
Glomerular filtration rate (mL/min/m2) 55.9 ± 25.5 61.4 ± 17.0 55.9 ± 19.6 50.0 ± 15.2 0.024
Previous pacemaker 14 (12.8%) 3 (11.1%) 9 (16.4%) 2 (7.4%) 0.570
Atrial fibrillation 27 (24.8%) 4 (14.8%) 19 (34.5%) 4 (14.8%) 0.064
Frailtyb 31 (28.4%) 5 (18.5%) 13 (23.6%) 13 (48.1%) 0.032
Ejection fraction (%) 56.8 ± 14.9 56.0 ± 14.9 58.0 ± 13.2 56.3 ± 10.4 0.250
Aortic valve area (cm2) 0.63 ± 0.16 0.63 ± 0.15 0.63 ± 0.16 0.64 ± 0.15 0.998
Aortic valve mean gradient (mm Hg) 45.4 ± 13.6 46.0 ± 13.3 44.9 ± 14.2 45.4 ± 13.0 0.386
Aortic valve maximal gradient (mm Hg) 76.2 ± 21.4 77.1 ± 20.8 74.2 ± 22.2 77.0 ± 20.5 0.286
CT mean annulus diameter (mm) 24.3 ± 2.7 24.3 ± 2.8 24.4 ± 2.5 24.2 ± 2.5 0.980
  1. Data are expressed as mean ± standard deviations (SD), median ( first quartile, third quartile) or number (%). Chi-square or Fisher test for categorical variables and t text or wilcoxon test for continuous variables
  2. aInterstitial lung disease or chronic obstructive pulmonary disease or asthma
  3. bAssessed based on serum albumin, gait speed, grip strength, and number of independent activities of daily leavingSuggested criteria for the diagnosis of frailty included 5-min walking time, grip strength, BMI < 20 kg/m2 and/or weight loss of 5 kg/year, serum albumin < 3.5 g/dL, and cognitive impairment or dementia