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Table 2 Perioperative data in the groups with no delirium, subsyndromal delirium, and clinical delirium

From: Risk factors for postoperative delirium on oxygen delivery-guided perfusion

Variable

No delirium (n = 53)

Subsyndromal delirium (n = 163)

Clinical delirium (n = 9)

P value

Overall

ND vs. SD

ND vs. CD

SD vs. CD

Surgical procedure

   

0.986

   

 Valve

41 (77.4%)

127 (77.9%)

8 (88.9%)

    

 Valve + TA replacement

6 (1.3%)

20 (12.3%)

1 (11.1%)

    

 TA replacement

1 (1.9%)

3 (1.8%)

0

    

 Adult congenital

1 (1.9%)

5 (3.1%)

0

    

 Cardiac tumor

4 (7.6%)

8 (4.9%)

0

    

Pump time (min)

127 (105–167)

128 (103–177)

173 (135–213)

0.110

   

Nadir DO2i (mL/min/m2)

292.2 ± 28.4

286.1 ± 28.5

278.3 ± 18.6

0.251

   

Median DO2i (mL/min/m2)

341.8 ± 20.9

339.9 ± 24.4

349.1 ± 25.9

0.488

   

AUC < DO2i300

42 (0–159)

68 (0–516)

265 (6–658)

0.246

   

Time < DO2i300 (min)

2.3 (0–6.8)

2.3 (0–11.7)

8 (0.5–10.7)

0.519

   

Median PI (L/min/m2)

2.72 (2.63–2.80)

2.78 (2.68–2.85)

2.86 (2.69–2.92)

0.012

0.025

0.118

0.415

Nadir Hct (%)

23 (21–24)

22 (21–23)

21 (20.5–22)

0.048

0.096

0.161

0.481

AUC < MAP60

571 (285–795)

620 (348–1151)

368 (235–729)

0.065

   

Time < MAP60 (min)

28.9 ± 31.5

31.7 ± 25.6

24.4 ± 19.7

0.635

   

Units of RBC transfused (u)

2.1 ± 4.1

2.4 ± 3.4

6.6 ± 3.7

0.003

0.872

0.003

0.003

Nadir ScO2 (%)

51 (43–58)

50 (42–56)

47.5 (41.5–55)

0.519

   

AUC < ScO280%bas

0 (0–4.5)

0 (0–28.6)

2.3 (0.0–114.9)

0.247

   

Time < ScO280%bas (min)

0 (0–2.4)

0 (0–15.2)

1.6 (0.1–40.8)

0.094

   

Intubation time (h)

6.7 (5.0–9.4)

6.2 (4.2–9.4)

15.2 (4.8–57.3)

0.123

   

Systolic blood pressure (mmHg)

118.7 ± 18.9

115.1 ± 21.1

123.9 ± 26.2

0.604

   

Blood glucose (mg/dL)

128 (110–148)

135 (118–152)

144 (131–187)

0.039

0.465

0.285

0.417

Sodium (mEq/L)

141.9 ± 3.4

142.7 ± 0.3

144.8 ± 2.7

0.026

0.283

0.045

0.162

Chloride (mEq/L)

107.0 ± 4.3

107.3 ± 4.2

109.2 ± 4.3

0.321

   
  1. Continuous and categorical data are expressed as means ± standard deviations or medians (interquartile ranges), and numbers (%), respectively. Nadir points were defined as the lowest points during measurement. The type of thoracic aortic replacement was ascending aortic replacement (excluded circulatory arrest under hypothermia). Systolic blood pressure, blood glucose, sodium, and chloride data were collected the day after surgery. AUC < MAP60, area under the curve below the 60 mmHg mean arterial pressure thresholds; AUC < DO2i300, area under the curve below the 300 mL/min/m2 oxygen delivery thresholds; AUC < ScO280%bas, area under the curve below the 80% of baseline cerebral oxygen saturation
  2. Time < MAP60, cumulative time below the 60 mmHg mean arterial pressure thresholds; Time < DO2i300, cumulative time below the 300 mL/min/m2 oxygen delivery thresholds; Time < ScO280%bas, cumulative time below the 80% of baseline cerebral oxygen saturation
  3. CD clinical delirium, DO2i oxygen delivery index, Hct hematocrit, ND no delirium, PI perfusion index, RBC red blood cell, ScO2 cerebral oxygen saturation, SD subsyndromal delirium, TA thoracic aortic
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Journal of Cardiothoracic Surgery

ISSN: 1749-8090

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