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Table 1 Demographics of patients according to the study groups

From: Impact of hyperbilirubinemia associated acute kidney injury on chronic kidney disease after aortic arch surgery: a retrospective study with follow-up of 1-year

Variable

Non-AKI (n = 97)

AKI without HB (n = 119)

HB-AKI (n = 68)

P

Age (y)

52.32 ± 11.36

52.77 ± 10.63

55.19 ± 11.35

0.225

BMI (kg/m2)

24.8 (22.9–27.0)

26.5 (29.1–24.1)

25.5 (23.7–28.4)

0.041

Male/Female

71/26

88/31

42/26

0.177

Hypertension (N, %)

55 (56.7%)

86 (72.3%)

45 (66.2%)

0.055

Diabetes (N, %)

6 (6.2%)

7 (5.9%)

9 (13.2%)

0.163

CHD (N, %)

10 (10.3%)

10 (8.4%)

6 (8.8%)

0.869

Smoking history (N, %)

46 (47.4%)

56 (47.1%)

23 (33.8%)

0.154

LVEF (%)

60.0 (60.0–61.0)

60.0 (60.0–61.0)

60.0 (60.0–62.0)

0.304

Previous heart surgery (N, %)

7 (7.2%)

8 (6.7%)

5 (7.4%)

1.000

Urgent surgery (N, %)

72 (74.2%)

97 (81.5%)

52 (76.5%)

0.449

Renal arteries arising from the false lumen (N, %)

43 (47.3%)

52 (43.7%)

20 (29.4%)

0.104

Main surgical procedure

Total arch replacement (N, %)

72 (74.2%)

96 (80.7%)

46 (67.6%)

0.140

Total arch replacement and FET (N, %)

18 (18.6%)

15 (12.6%)

14 (20.6%)

0.295

Hemiarch replacement (N, %)

7 (7.2%)

8 (6.7%)

8 (11.8%)

0.487

Concomitant procedures

Bentall (N, %)

58 (59.8%)

58 (48.7%)

43 (63.2%)

0.101

Ascending aorta replacement (N, %)

39 (40.2%)

62 (52.1%)

30 (44.1%)

0.204

CABG (N, %)

7 (7.2%)

13 (10.9%)

6 (8.8%)

0.677

Valve surgery (N, %)

8 (8.2%)

3 (2.5%)

4 (5.9%)

0.154

Basic laboratory characteristics

AST (IU/L)

22.0 (17.3–37.0)

26.0 (19.0–51.9)

25.0 (16.0–40.0)

0.216

ALT (IU/L)

25.0 (16.0–36.0)

30.2 (20.0–49.3)

27.0 (19.3–39.0)

0.219

Total bilirubin (μmol/L)

21.8 (17.1–31.2)

18.6 (14.3–25.3)

24.2 (18.5–37.3)

 < 0.001

Direct bilirubin (μmol/L)

7.7 (5.3–10.7)

5.8 (4.4–8.1)

7.9 (5.9–10.2)

0.151

Albumin (g/L)

37.28 ± 4.69

38.36 ± 4.32

36.63 ± 4.98

0.040

sCr (μmol/L)

80.7 (68.6–104.0)

77.4 (62.0–98.0)

74.8 (58.7–103.2)

0.477

BUN (μmol/L)

7.0 (5.4–8.5)

7.1 (5.4–8.7)

6.6 (5.0–9.3)

0.985

  1. AKI acute kidney injury; HB hyperbilirubinemia; BMI body mass index; CHD coronary heart disease; LVEF left ventricular ejection fraction; FET frozen elephant trunk; CABG coronary artery bypass grafting; AST aspartate transaminase; ALT alanine aminotransferase; sCr serum creatinine; BUN blood urea nitrogen