Table 1 REFORM-MR inclusion/exclusion criteria

Presence of FMR with impaired movement of leaflets during systole (type IIIb)—effective regurgitation orifice area greater than 20 mm²/regurgitant volume more than 30 ml/beat

Prolapse of anterior or posterior mitral valve leaflet (type II MR)

Left ventricular ejection fraction < 50% and/or left ventricular end-diastolic diameter ≥ 55 mm

Combined procedure with simultaneous aortic valve surgery

Tenting of the posterior and/or anterior mitral leaflet > 10 mm

Redo surgery of the mitral valve

Previous coronary artery bypass graft (CABG) or valvular surgery (aortic, mitral, tricuspid)

Degenerative mitral valve disease (e.g., extensive annulus calcification or leaflet/chordae fibrosis/restriction)

Type I MR without leaflet tethering (i.e., atrial FMR)