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Table 3 Association between clinical factors and obesity/morbid obesity among T(A)AD inpatients

From: Morbid obesity impacts mortality among inpatients with type a aortic dissection: an analysis of the national inpatient sample

Variables

Effect

Non-obese

Univariate model 1

Multivariable model 2a

Obesity

Morbid obesity

Obesity

Morbid obesity

Ref

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

Age

18–44 versus 45–64

Ref

1.05 (0.85,1.30)

0.636

0.54 (0.44,0.68)

< 0.001

0.87 (0.70,1.08)

0.212

0.44 (0.35,0.56)

< 0.001

 

18–44 versus 65–74

Ref

0.80 (0.62,1.03)

0.086

0.34 (0.25,0.45)

< 0.001

0.55 (0.42,0.72)

< 0.001

0.21 (0.15,0.29)

< 0.001

 

18–44 versus ≥ 75

Ref

0.44 (0.32,0.60)

< 0.001

0.12 (0.07,0.19)

< 0.001

0.29 (0.21,0.40)

< 0.001

0.07 (0.04,0.11)

< 0.001

Sex

Male–female

Ref

1.01 (0.87,1.17)

0.898

1.35 (1.11,1.65)

0.003

1.13 (0.97,1.32)

0.118

1.66 (1.34,2.06)

< 0.001

Race

White–Black

Ref

1.13 (0.93,1.37)

0.209

1.86 (1.46,2.37)

< 0.001

0.91 (0.75,1.11)

0.366

1.28 (0.98,1.68)

0.075

 

White–Hispanic

Ref

1.17 (0.85,1.60)

0.327

1.53 (1.04,2.25)

0.031

0.94 (0.69,1.29)

0.702

1.01 (0.66,1.54)

0.970

 

White–other

Ref

0.77 (0.61,0.98)

0.034

0.99 (0.74,1.32)

0.924

0.73 (0.58,0.93)

0.011

0.84 (0.62,1.15)

0.274

Dyslipidemia

 

Ref

1.59 (1.37,1.86)

< 0.001

1.33 (1.10,1.62)

0.004

1.50 (1.26,1.77)

< 0.001

1.59 (1.26,1.99)

< 0.001

Congestive heart failure

 

Ref

1.17 (0.72,1.88)

0.527

1.90 (1.16,3.12)

0.011

1.26 (0.78,2.05)

0.349

1.80 (1.04,3.14)

0.037

Depression

 

Ref

1.61 (1.25,2.07)

< 0.001

1.09 (0.72,1.64)

0.686

1.40 (1.08,1.82)

0.011

1.02 (0.67,1.56)

0.923

Diabetes, uncomplicated

 

Ref

2.15 (1.76,2.63)

< 0.001

2.65 (2.07,3.41)

< 0.001

2.05 (1.66,2.54)

< 0.001

2.83 (2.15,3.73)

< 0.001

Diabetes with chronic complications

 

Ref

2.13 (1.40,3.23)

< 0.001

2.29 (1.42,3.71)

0.001

2.23 (1.45,3.42)

< 0.001

2.45 (1.46,4.10)

< 0.001

Drug abuse

 

Ref

0.85 (0.59,1.22)

0.376

0.41 (0.21,0.79)

0.008

0.75 (0.51,1.11)

0.149

0.30 (0.15,0.60)

< 0.001

Hypertension (combine uncomplicated and complicated)

 

Ref

1.86 (1.52,2.26)

< 0.001

1.34 (1.06,1.68)

0.014

1.68 (1.36,2.06)

< 0.001

1.24 (0.97,1.59)

0.089

Fluid and electrolyte disorders

 

Ref

1.12 (0.96,1.31)

0.151

1.31 (1.07,1.60)

0.008

1.12 (0.96,1.31)

0.155

1.27 (1.03,1.56)

0.027

  1. OR, odds ratio; CI, confidence interval; T(A)AD, type A thoracic aortic dissection
  2. aMultivariable model 2: adjusted for age, sex, race, dyslipidaemia, long-term anticoagulants and antithrombotics, smoking, alcohol abuse, deficiency anemia, chronic blood loss anemia, congestive heart failure, depression, diabetes, drug abuse, hypertension, hypothyroidism, lymphoma, fluid and electrolyte disorders, renal failure.