Table 2 Univariate analysis of prognostic factors associated with disease-free survival and overall survival
Treatment | Surgery (n = 50) | Chemotherapy (n = 22) | |
|---|---|---|---|
| Â | DFS rate (%) | OS rate (%) | OS rate (%) |
Characteristic, factor | Factor /No factor (p value) | Factor /No factor (p value) | Factor /No factor (p value) |
Age, > 70 y | 53/67 (0.668) | 48/78 (0.100) | 0/34 (0.544) |
Sex, male | 33/34 (0.580) | 58/70 (0.943) | 22/34 (0.286) |
Extrapulmonary metastasectomy | 19/35 (0.824) | 63/65 (0.453) | 27/26 (0.434) |
CRC location, rectum | 14/47 (0.017) | 53/71 (0.236) | 0/50 (0.013) |
CRC tumor size, > 40Â mm | 29/42 (0.241) | 54/77 (0.232) | 18/32 (0.099) |
CRC pT factor, 4/3/2/1/0 | 32/43/13/100 (0.127) | 55/78/50/100 (0.565) | 0/28/67/0 (0.37) |
CRC pN factor, 1–3/0 | 28/41 (0.171) | 56/76 (0.244) | 20/50 (0.080) |
CRC pStage, IV/III/II/I | 36/31/45/29 (0.726) | 63/86/67/44 (0.404) | - |
Synchronicity of PM | 29/35 (0.639) | 55/70 (0.150) | 40/0 (0.608) |
DFI, < 1 year | 33/33 (0.584) | 62/69 (0.669) | 30/31 (0.64) |
LM size, > 20Â mm | 46/27 (0.135) | 61/67 (0.628) | - |
LM size, > 10Â mm | - | - | 0/36 (0.285) |
LM number, multiple | 29/39 (0.296) | 36/79 (0.012) | - |
LM number, > 4 | - | - | 41/15 (0.597) |
Bilaterality of LM, bilateral | 50/31 (0.631) | 100/61 (0.129) | 36/0 (0.056) |
Pretreatment CEA, > 5 ng/ml | 41/27 (0.182) | 57/68 (0.551) | 29/23 (0.424) |
Perioperative chemotherapy for LM | 50/23 (0.067) | 72/59 (0.171) | - |
Surgical procedure, lobectomy | 44/28 (0.537) | 57/69 (0.980) | - |
Use of molecular targeted drugs | - | - | 35/26 (0.62) |