Fig. 5
From: Unusual presentation and delayed diagnosis of cardiac angiosarcoma
Pathology findings demonstrating angiosarcoma. A low power magnification (× 12.5) hematoxylin and eosin staining of pseudoaneurysm reveals fibrin and organizing hematoma with a variably cellular fibrous cyst wall. B High power magnification (× 400) of pseudoaneurysm reveals scattered enlarged pleomorphic tumor cells with rare atypical mitoses in the background of abundant reactive granulation tissue. C Cardiophrenic nodule (× 400) shows similar atypical cells with unequivocal anaplasia and poorly-formed vascular lumina. D Cardiophrenic nodule (× 400) shows malignant endothelial cells with endothelial hobnailing into the vascular lumen