Volume 10 Supplement 1

Proceedings of the WSCTS 25th Anniversary Congress

Open Access

Is perioperative pro-B-type natriuretic peptide a good tool to evaluate surgical risk in cardiac surgery?

  • Marta Matamala1,
  • Neslim Gálvez1,
  • Elisa Ochoa1,
  • Ana Barral1,
  • Javier Fañanás1,
  • Jose María Vallejo1,
  • Manuel Vázquez1,
  • Fernando Sorribas1 and
  • Carlos Ballester1
Journal of Cardiothoracic Surgery201510(Suppl 1):A128

https://doi.org/10.1186/1749-8090-10-S1-A128

Published: 16 December 2015

Background/Introduction

Predicting major adverse events and death in patients undergoing cardiac surgery is based on clinical risk scores such as Euroscore. This score has a moderate power for discriminating morbidity. Natriuretic peptides are well-established biomarkers in numerous clinical settings, prognostic, diagnostic and treatment of cardiac failure. In cardiac surgical patients the role of natriuretic peptides as risk markers is less well delineated.

Aims/Objectives

To assess the utility of natriuretic peptides as risk markers in cardiac surgery

Method

This study is a prospective longitudinal study of consecutive 135 patients undergoing on-pump cardiac surgery between 2012 and 2013. We evaluated preoperative euroSCORE II, preoperative and 24 h postoperative pro-BNP. The endpoints were: heart failure, renal failure, all-cause mortality at 12 months. Independent sample t-Test were performed.

Results

One hundred thirty-five patients were available for analysis. the mean EuroSCORE II was 2,49%. Fourteen patients (10%) experienced postoperative heart failure and 30 patients (22%) renal failure. Within 12 months after surgery, six patients died. The "t" test showed significant augmentation of preoperative and postoperative pro-BNP in relation to heart and kidney failure.

Discussion/Conclusion

Increased perioperative pro-BNP concentrations are associated with more incidence of postoperative heart failure and renal insufficiency. Elevated preoperative pro-BNP is not correlated with mortality. Postoperative pro-BNP adds little to the value of preoperative pro-BNP measurement alone.

Authors’ Affiliations

(1)
Left a Servicio de Cirugía Cardiovascular, Hospital Universitario Miguel Servet

Copyright

© Matamala et al. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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