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The use of Tissue PatchTM to Reduce the Duration of Air Leak Following Lung Volume Reduction Surgery.


Prolonged post-operative air leak is a recognised complication in patients receiving lung volume reduction surgery (LVRS). Some patients are transferred to a portable flutter-valve bag to facilitate discharge. TissuePatchTM is a synthetic absorbable self-adhesive film which acts as an adjunct to minimise air leak.


Our aim was to see whether the use of TissuePatchTM would reduce post-operative air leak and the subsequent need for a drain in LVRS patients.


We retrospectively analysed LVRS cases over a two year period performed by a single surgeon to minimise procedural heterogeneity. Patients were divided into two groups; group 1 received Tissue PatchTM as the staple line adjunct and group 2 did not.


There were 26 cases in total (one excluded due to in hospital death); group 1=12 (2= bilateral procedures, 10=upper lobe procedures, median age 65), group 2=13 (all unilateral, all upper lobe procedures, median age 63). The median length of stay was 15 for both groups (p = 0.40). The median duration of air leak was 13 days for group 1 and 18 days for group 2 (p = 0.95). Only 2/12 (16%) in group 1 did not have full resolution of air leak and drain removal prior to discharge and were placed on a portable flutter-valve bag compared to 5/13 (38%) in group 2 (p = 0.64).


We have observed a reduced trend in the number of patients being discharged with persistent air leak following LVRS with the concomitant use of Tissue PatchTM. A larger study is indicated which may demonstrate significant results.

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This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.

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Monaghan, A., Joshi, V. & Rathinam, S. The use of Tissue PatchTM to Reduce the Duration of Air Leak Following Lung Volume Reduction Surgery.. J Cardiothorac Surg 10 (Suppl 1), A13 (2015).

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