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  • Meeting abstract
  • Open Access

Comparison of myocardial protection methods in mitral valve surgery: a cohort study

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Journal of Cardiothoracic Surgery201510 (Suppl 1) :A171

  • Published:


  • Ischemia
  • Cardiopulmonary Bypass
  • Ischemia Time
  • Intubation Time
  • Vasoactive Drug


Myocardial protection is the group of strategies aimed at reducing ischemia-reperfusion lesions and its consequences. There is much discussion regarding different methods and their features, while there is no unanimity about which is most appropriate.


We aimed to compare two types of myocardial protection, intermittent global ischemia and cold crystalloid cardioplegia, in patients submitted to mitral valve surgery: preoperative conditions and surgical or clinical outcomes. Furthermore, we aimed to calculate cardioplegia exclusive equipments' price.


We performed a retrospective cohort study of medical records from patients who underwent mitral valve surgery at Hospital Universitário Ciências Médicas between 2010 and 2014. We compared preoperative conditions (gender, age and Euroscore II) and outcomes: death within 30 days, postoperative intensive care time and hospital stay time, cardiopulmonary bypass and ischemia time, use of pacemaker, use of vasoactive drugs and their time and intubation time. Cardioplegia equipments' total cost was calculated by indexation through three methods and thereafter the mean of its results.


We found no differences between the two groups' preoperative conditions. The only difference between outcomes were cardiopulmonary bypass and myocardial ischemia time, in which the intermittent global ischemia group was favored (Bypass: RR 0,19, 95% CI: 0,09 - 0,41; Ischemia: RR 0,20, 95% CI: 0,10 - 0,43).The mean price found for the cardioplegia equipment was R$321,03 (USD 101,12).


Intermittent global ischemia presented shorter surgical duration and reduced mitral valve surgery costs, while it didn't affect mortality or morbidity. More comparative studies including other surgery types and different services are necessary to validate our results.

Authors’ Affiliations

Cardiovascular Surgery, Hospital Universitário Ciências Médicas, Belo Horizonte, Minas Gerais, 30140-073, Brazil
Faculdade da Saúde e Ecologia Humana, Vespasiano, Minas Gerais, 33200-000, Brazil


© Rocha et al. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.