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Evaluate the outcome of pneumonectomy for stage III a-N2 NSCLC
Journal of Cardiothoracic Surgery volume 10, Article number: A206 (2015)
The effect of surgery in patients with III a-N2 non-small cell lung cancer is not certain.
We intend to evaluate the outcome of pneumonectomy in III a-N2 non-small cell lung cancer.
We retrospectively reviewed the cases of patients with III a-N2 non-small cell lung cancer, who underwent pneumonectomy from April 2003 to January 2014 at a single institution.
During the study, 184 patients underwent surgical resection of stage III a-N2 non-small cell lung cancer. Among them, 35 patients had pneumonectomy, 29 patients (83%) were male, and 6 (17%) were female. The median age was 57 years (43 yrs-77 yrs) old, and the median follow up duration was 77 month. 27 patients (77%) had induction chemotherapy before operation. Right pneumonectomy was performed in 13 patients (37%), and Left pneumonectomy was done in 22 patients (63%). The 5-year survival was 58% in pneumonectomy, 28% in the right pneumonectomy and 76% in the left pneumonectomy, respectively. Left pneumonectomy(p = 0.021) and complete resectability (p = 0.017) were positive prognostic factor, but the induction chemotherapy before operation was negative prognostic factor. (p = 0.040)
The side of operation and complete resectability are positive prognostic factor, but the induction chemotherapy is negative prognostic factor for pneumonectomy in III a-N2 NSCLC patients.
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Park, S., Jang, HJ., Yi, E. et al. Evaluate the outcome of pneumonectomy for stage III a-N2 NSCLC. J Cardiothorac Surg 10, A206 (2015). https://doi.org/10.1186/1749-8090-10-S1-A206
- Public Health
- Lung Cancer
- Prognostic Factor
- Cardiac Surgery
- Surgical Resection