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  • Meeting abstract
  • Open Access

Evaluate the outcome of pneumonectomy for stage III a-N2 NSCLC

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Journal of Cardiothoracic Surgery201510 (Suppl 1) :A206

https://doi.org/10.1186/1749-8090-10-S1-A206

  • Published:

Keywords

  • Public Health
  • Lung Cancer
  • Prognostic Factor
  • Cardiac Surgery
  • Surgical Resection

Background/Introduction

The effect of surgery in patients with III a-N2 non-small cell lung cancer is not certain.

Aims/Objectives

We intend to evaluate the outcome of pneumonectomy in III a-N2 non-small cell lung cancer.

Method

We retrospectively reviewed the cases of patients with III a-N2 non-small cell lung cancer, who underwent pneumonectomy from April 2003 to January 2014 at a single institution.

Results

During the study, 184 patients underwent surgical resection of stage III a-N2 non-small cell lung cancer. Among them, 35 patients had pneumonectomy, 29 patients (83%) were male, and 6 (17%) were female. The median age was 57 years (43 yrs-77 yrs) old, and the median follow up duration was 77 month. 27 patients (77%) had induction chemotherapy before operation. Right pneumonectomy was performed in 13 patients (37%), and Left pneumonectomy was done in 22 patients (63%). The 5-year survival was 58% in pneumonectomy, 28% in the right pneumonectomy and 76% in the left pneumonectomy, respectively. Left pneumonectomy(p = 0.021) and complete resectability (p = 0.017) were positive prognostic factor, but the induction chemotherapy before operation was negative prognostic factor. (p = 0.040)

Discussion/Conclusion

The side of operation and complete resectability are positive prognostic factor, but the induction chemotherapy is negative prognostic factor for pneumonectomy in III a-N2 NSCLC patients.

Authors’ Affiliations

(1)
Department of Thoracic and Cardiovascular Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, 166 Gumi-ro, Bundang-gu, Seongnam-si, Gyeonggi-do, 463-707, Seoul, Korea

Copyright

© Park et al. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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