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Comparison of long-term outcomes between Off-Pump CABG and conventional CABG


There has been controversy surrounding the late outcomes of Off-Pump Coronary Artery Bypass (OPCAB).


The aim of this study was to compare the early and long-term outcomes of OPCAB with those of conventional CABG (c-CABG).


This retrospective study was based on data from 183 patients who underwent CABG between January, 2000 and December, 2005. OPCAB was performed in 102 patients and c-CABG in 81. The mean follow-up duration was 107 months. The end-points of long-term results were overall death, freedom from cardiac death and major adverse cardiac events (MACE). We expressed the Kaplan-Meyer survival curve, and determined the independent predictors for risk factors of mortality using multi-variate analysis.


Four patients in c-CABG group died of low cardiac output syndrome and CVA. There was no operative mortalities in OPCAB group (p = .023). Bleeding requiring reopening (5:1, p = .05) and CVA (3:0, p = .05) occurred more frequently in c-CABG group than OPCAB group. The completeness of follow-up was 83.8%.

Late deaths occurred in 26 patients (11 [18.0%] in c-CABG group, 15 [16.9%] in OPCAB group). The causes of death were cancer, CVA, cardiac and sepsis.

Rerevascularization was performed more frequently in OPCAB group than in c-CABG group (14:5, p = .297). Five-year overall survival, freedom from cardiac death and MACE in c-CABG and OPCAB groups were 90.2 vs 96.6 %, 98.4 vs 100 %, and 91.8 vs 85.4 %, respectively. Ten-year survival estimates were 82.0 vs 83.1 %, 96.7 vs 96.6 %, and 88.5 vs 83.1 %, respectively. There were no statistical significance between 2 groups' survival (p = .743 in overall survival, P = .813 in free from cardiac death, and p = .305 in free from MACE). Age was an independent predictor for mortalities (p = 0.000).


OPCAB showed the better operative mortality and complication rates, and the higher rerevascularization rate, compared with c-CABG. Nevertheless, the survival indices did not reveal the statistical significance between 2 groups.

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This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.

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Lee, W.Y., Lim, J.H., Kim, K.I. et al. Comparison of long-term outcomes between Off-Pump CABG and conventional CABG. J Cardiothorac Surg 10 (Suppl 1), A243 (2015).

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