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A Retrospective Cohort Study in patients over 55: Mechanical versus Biological valve prostheses


The choice between a mechanical valve and a biological valve is not always clear for patients requiring valve replacement surgery; age has been considered to be the determining factor in the decision making process. Previous guidelines have recommended the implantation of mechanical prostheses in patients under the age of 65 and biological prostheses in those over 65.


To investigate the life expectancy of patients over 55 who have had either a bioprosthetic or mechanical valve replacement and to establish if there is a significant difference in survival rates between these two valve groups. In addition, this research aims to investigate if factors such as hypertension, diabetes and a history smoking have an impact on the patients' survival.


138 patient charts meeting the inclusion criteria, were identified using the percussionist database, and were used to extract the data relevant to the study. Data was analysed using SPSS.


Of the 138 patients, 59.8% (n = 61) of the patients with biological valves and 58.3% (n = 21) of the patients with mechanical survived between 5 to 10 years. The unpaired t-test and the chi-squared test performed showed that there was no statistically significant difference in the survival of patients who had biological valves and those who had mechanical valves.


This study suggests that the type of valve prosthesis implanted does not affect the survival of the patients.

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This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.

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Tarazi, M., Sivabalah, K., Mayooran, N. et al. A Retrospective Cohort Study in patients over 55: Mechanical versus Biological valve prostheses. J Cardiothorac Surg 10 (Suppl 1), A345 (2015).

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