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Table 2 Cell death status over time

From: Influence of hypothermia on right atrial cardiomyocyte apoptosis in patients undergoing aortic valve replacement

 

Basal (ModHT group/MiHT group)

Reperfusion (ModHT group/MiHT group)

p Value (ModHT group/MiHT group)

Non apoptotic non necrotic cells (annexin negative, PI negative) (%)

73.86 ± 18.49/67.28 ± 16.40

51.20 ± 23.88/71.71 ± 11.35 a

0.002/0.307

Early apoptotic cells (annexin positive, PI negative) (%)

16.45 ± 13.36/20.70 ± 12.21

33.21 ± 17.85/17.62 ± 8.06 a

0.003/0.180

Late apoptotic or necrotic cells (annexin positive, PI positive) (%)

6.97 ± 3.68/10.49 ± 5.92

11.45 ± 5.11/8.90 ± 5.36

0.009/0.513

Fas positive cells (%)

15.14 ± 17.85/20.03 ± 14.99

31.34 ± 22.54/14.30 ± 10.66

0.009/0.081

CK (IU/L)

53.1 ± 21.6/60.2 ± 23.7

167.1 ± 158.5/153.8 ± 87.9

0.045/0.011

CK-MB (IU/L)

29.13 ± 18.20/20.00 ± 3.62

42.25 ± 33.80/37.70 ± 12.18

0.355/0.001

LDH (IU/L)

363.0 ± 94.2/334.5 ± 61.6

385.4 ± 152.7/363.5 ± 80.1

0.723/0.240

Troponin I (μg/L)

0.32 ± 0.33/0.22 ± 0.15

1.48 ± 1.37/1.45 ± 0.53

0.029/< 0.001

Lactate (mmol/L)

1.53 ± 0.88/1.62 ± 0.91

3.60 ± 1.32/3.19 ± 1.19

0.002/0.005

  1. Results are expressed as means ± standard deviations.
  2. a p < 0.05 compared to ModHT group.
  3. CK, creatine kinase; CK-MB, creatine kinase myocardial band; LDH, lactate dehydrogenase; PI, propidium iodide.