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Table 1 Baseline patient and tumor characteristics of pulmonary metastasectomies performed from January 1986 to November 2006

From: Video-assisted thoracic surgery (VATS) as a safe alternative for the resection of pulmonary metastases: a retrospective cohort study

 

All (n = 171)

OPEN (n = 135)

VATS (n = 36)

p-value†

Age (in years)*

   

< 0.01†

   Median (Interquartile range)

53 (43–63)

49 (40–61)

58.5 (50.5–71)

 

   95% C.I.

49 to 56

47 to 55.25

52.85 to 66.29

 

Sex

   

0.26

   Female

71 (41.5)

53 (39.3)

18 (50)

 

   Male

100 (58.5)

82 (60.7)

18 (50)

 

Race

   

0.06

   Caucasian

140 (81.9)

112 (83.0)

28 (78)

 

   non-Caucasian

31 (18.1)

23 (17)

8 (22)

 

Comorbidities

    

   Single

61 (35.7)

45 (33.3)

16 (44)

0.24

   3 comorbidities

10 (5.8)

5 (3.7)

5 (14)

0.04†

   Smoker

62 (36.3)

47 (34.8)

15 (41.7)

0.44

Primary Tumor Type

   

< 0.01†

   Bladder

3 (1.8)

2 (1.5)

1 (3)

 

   Breast AC

9 (5.3)

5 (3.7)

4 (11)

 

   Colorectal AC

26 (15.2)

14 (10.4)

12 (33)

 

   Head/Neck

4 (2.3)

3 (2.2)

1 (3)

 

   Melanoma

14 (8.2)

6 (4.4)

8 (22)

 

   Renal cell

22 (12.9)

21 (15.6)

1 (3)

 

   Sarcoma

81 (47.4)

73 (54.1)

8 (22)

 

   Testicular

5 (2.9)

5 (3.7)

-

 

   Other

7 (4.1)

6 (4.4)

1 (3)

 

Adjuvant therapy

    

   Chemotherapy

129 (75.4)

106 (78.5)

23 (64)

0.08

   Radiation

73 (42.7)

54 (40)

19 (53)

0.19

Laterality

   

< 0.01†

   Unilateral

124 (72.5)

90 (66.7)

34 (94)

 

   Bilateral

47 (27.5)

45 (33.3)

2 (6)

 

Magnitude

   

0.06

   Wedge resection

118 (69)

88 (65.2)

30 (83)

 

   All other

53 (31)

47 (34.8)

6 (16.7)

 

Number of lesions

   

< 0.01†

   Single

48 (28.1)

28 (20.7)

20 (56)

 

   2–5

94 (55)

79 (58.5)

15 (42)

 

   > 5

29 (17)

28 (20.7)

1 (3)

 

Metastatic Occurrences

   

0.15

   1

102 (59.6)

76 (56.3)

26 (72)

 

   2

38 (22.2)

31 (23)

7 (19)

 

   3+

31 (18.1)

28 (20.7)

3 (8)

 

Deaths

74 (43)

65 (48)

9 (25)

0.02†

  1. *All characteristics are expressed as no. (%), unless specified otherwise. Some covariables were grouped to preserve a 10% number of patients in each category for analysis. Non-Caucasian includes: Asian (10 OPEN; 7 VATS), Black (4 OPEN; 1 VATS) and Latino (9 OPEN; 0 VATS). All other includes: segmentectomy (17 OPEN; 4 VATS), lobectomy (29 OPEN; 2 VATS) and pneumonectomy (1 OPEN; 0 VATS). When PTT was categorized into carcinoma (includes bladder, breast, colorectal, melanoma, head/neck, renal cell, testicular, and 3 other type) and sarcoma (includes sarcoma and 3 other type), a statistical difference remained (p < 0.001). † Pearson χ2 or Fisher exact; two-tailed p-value < 0.05 considered statistically significant.