Dramatic SMC loss occurs by 1d post transplant. (a) and (b) native C3H aorta; (c) and (d) native C3H aorta after 20 min cold storage (pre-transplant); (e) and (f) C3H allograft transplanted into B6 recipient harvested at 1d post-transplant. Arrow heads demarcate the media. Red arrows indicate medial SMC. IEL = internal elastic lamina. SMC = smooth muscle cell. EC = endothelial cell. NФ = neutrophil.