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Table 1 Hemodynamic measurements and statically analysis

From: Acute pressure overload of the right ventricle. Comparison of two models of right-left shunt. Pulmonary artery to left atrium and right atrium to left atrium: experimental study

  

baseline mean ± SD

10 min mean ± SD

20 min mean ± SD

% change baseline-10 min median

% change baseline-20 min median

Pulse (b/min)

Shunt PA -LΑ

95.67 ± 10.45

112.80 ± 9.71**

105.20 ± 16.90

18.75

9.28

 

Shunt RA -LΑ

95.67 ± 10.45

106.87 ± 18.31*

103.80 ± 13.52

8.69

9.18

 

p-value

NS

NS

NS

NS

NS

Arterial Blood pressure (mean)

Shunt PA -LΑ

64.67 ± 6,72

59.33 ± 14.02 **

49.87 ± 10.08 **

-6.34

-20.31

 

Shunt RA -LΑ

64.67 ± 6,72

59.20 ± 10.71

58.60 ± 13.43

-7.04

-14.23

 

p-value

NS

NS

0.054

NS

NS

Right Ventricular pressure (mean)

Shunt PA -LΑ

30.00 ± 4.42

15.93 ± 4.73**

12.53 ± 4.49**

-50.0

-60.0

 

Shunt RA -LΑ

30.00 ± 4.42

10.87 ± 3.60**

13.5 ± 5.12**

-64.0

-65.0

 

p-value

NS

0.022

NS

0.074

NS

Central Venous pressure (mean)

Shunt PA -LΑ

6.93 ± 2.40

5.21 ± 2.99*

5.12 ± 3.00

-25.0

0.0

 

Shunt RA -LΑ

6.93 ± 2.40

6.53 ± 2.72$

3.46 ± 3.52*

0.0

-50.0

 

p-value

NS

NS

NS

NS

NS

Left Atrial pressure (mean)

Shunt PA -LΑ

5.67 ± 3.29

5.93 ± 3.51

5.93 ± 3.10

0.0

0.0

 

Shunt RA -LΑ

5.67 ± 3.29

4.73 ± 3.03

4.47 ± 3.02

0.0

-18.0

 

p-value

NS

NS

NS

NS

NS

Pulmonary artery pressure (proximal)

Shunt PA -LΑ

36.73 ± 5.28

21.73 ± 8.91**

21.63 ± 92.28**

-40.0

-40.0

 

Shunt RA -LΑ

36.87 ± 4.70

29.03 ± 8.10**

28.90 ± 8.10**

-20.0

-21.0

 

p-value

NS

NS

NS

NS

NS

Pulmonary artery pressure (distal)

Shunt PA -LΑ

12.73 ± 5.28

12.47 ± 4.81

12.40 ± 4.61

0.0

0.0

 

Shunt RA -LΑ

17.13 ± 5.25

16.80 ± 4.83

17.27 ± 5.36

0.0

0.0

 

p-value

NS

NS

NS

NS

NS

Shunt pressure

Shunt PA -LΑ

 

19.60 ± 4.94

19.93 ± 4.83

 

-5.0

 

Shunt RA -LΑ

 

5.53 ± 1.40

4.87 ± 1.36

 

-14.3

 

p-value

 

p < 0,0005

p < 0,0005

 

0.023

CO

Shunt PA -LΑ

4.93 ± 0.90

5.19 ± 1.22

5.39 ± 1.34

3.92

14.03

 

Shunt RA -LΑ

4.93 ± 0.90

4.64 ± 1.02

4.87 ± 1.13

-7.69

-2.33

 

p-value

NS

NS

NS

NS

NS

SVR

Shunt PA -LΑ

962.02 ± 153.04

847.17 ± 207.17*$

667.97 ± 207.64**

-15.44

-29.90

 

Shunt RA -LΑ

962.02 ± 153.04

891.98 ± 221.52

815.47 ± 213.14**

-6.20

-14.81

 

p-value

NS

NS

0.075

NS

0.021

Flow LAD

Shunt PA -LΑ

18.43 ± 6.83

16.14 ± 4.28

20.93 ± 7.35

-8.3

9.1

 

Shunt RA -LΑ

18.43 ± 6.83

14.64 ± 5.37*

10.79 ± 4.98**

-28.0

-33.3

 

p-value

NS

NS

p < 0,0005

NS

p < 0,0005

  1. ** p < 0.005 vs. baseline, * p < 0.05 vs. baseline, $ p < 0.05 vs. 20 min