Skip to main content

Table 2 A summary of lung function, gas exchange, DLCO% and 6MWD of five RCTs on the 3rd, 6th, 12th postoperative month

From: Several clinical interests regarding lung volume reduction surgery for severe emphysema: meta-analysis and systematic review of randomized controlled trials

Variables Postoperative follow-up (month) No of RCTs No of total patients GroupA/B WMD95%CI p-value
  3 2[12, 16] 80 39/41 0.23(0.08,0.37) 0.002
FEV1 6 3[2, 17, 19] 180 89/91 0.32(0.23,0.41) <0.00001
  12 3[2, 17, 19] 169 65/64 0.28(0.20,0.36) <0.00001
  3 2[12, 16] 80 39/41 11.31(6.29,15.69) <0.00001
FEV1% 6 3[2, 17, 19] 180 89/91 10.16(7.42,12.89) <0.00001
  12 3[2, 17, 19] 167 85/82 7.65(4.97,10.33) <0.00001
  3 2[12, 16] 80 39/41 -54.44(-75.23, -33.85) <0.00001
RV% 6 3[2, 17, 19] 170 87/83 - 54.09( - 64.66, -43.52) <0.00001
  12 3[2, 17, 19] 166 86/80 - 53.42( - 63.74, -43.10) <0.00001
TLC% 3 2[12, 16] 80 39/41 - 21.70( - 30.98, -12.42) <0.00001
  6 2[2, 19] 115 59/56 - 15.73( - 22.44, -9.02) <0.00001
  12 3[2, 17, 19] 120 59/61 - 16.24( - 23.07, -9.41) <0.00001
DLCO% 6 2[17, 19] 105 52/53 0.01(-0.25,0.27) 0.95
  12 2[17, 19] 96 51/45 0.01(-0.25,0.27) 0.25
Pa02 6 2[17, 19] 136 67/6 9.98(9.65,10.13) <0.00001
  12 2[2, 17] 114 60/54 6.37(6.10,6.64) <0.00001
PaC02 6 4[2, 11, 17, 21] 229 108/121 - 1.54(- 1.72, - 1.36) <0.00001
  12 2[2, 17] 114 60/54 -2.00(-2.23, -1.77) <0.00001
  3 2[12, 16] 80 39/41 10.5(-16.30,37.38) 0.44
6MWD 6 5[2, 11, 17, 19, 21] 274 129/145 68.34(36.58,100.09) <0.00001
  12 3[2, 17, 19] 168 85/83 76.92(60.87,92.98) <0.00001