Table 2 A summary of lung function, gas exchange, DLCO% and 6MWD of five RCTs on the 3^rd, 6^th, 12^th postoperative month

3

2[12, 16]

80

39/41

0.23(0.08,0.37)

0.002

FEV1

6

3[2, 17, 19]

180

89/91

0.32(0.23,0.41)

<0.00001

12

3[2, 17, 19]

169

65/64

0.28(0.20,0.36)

<0.00001

3

2[12, 16]

80

39/41

11.31(6.29,15.69)

<0.00001

FEV1%

6

3[2, 17, 19]

180

89/91

10.16(7.42,12.89)

<0.00001

12

3[2, 17, 19]

167

85/82

7.65(4.97,10.33)

<0.00001

3

2[12, 16]

80

39/41

-54.44(-75.23, -33.85)

<0.00001

RV%

6

3[2, 17, 19]

170

87/83

- 54.09( - 64.66, -43.52)

<0.00001

12

3[2, 17, 19]

166

86/80

- 53.42( - 63.74, -43.10)

<0.00001

TLC%

3

2[12, 16]

80

39/41

- 21.70( - 30.98, -12.42)

<0.00001

6

2[2, 19]

115

59/56

- 15.73( - 22.44, -9.02)

<0.00001

12

3[2, 17, 19]

120

59/61

- 16.24( - 23.07, -9.41)

<0.00001

DLCO%

6

2[17, 19]

105

52/53

0.01(-0.25,0.27)

0.95

12

2[17, 19]

96

51/45

0.01(-0.25,0.27)

0.25

Pa02

6

2[17, 19]

136

67/6

9.98(9.65,10.13)

<0.00001

12

2[2, 17]

114

60/54

6.37(6.10,6.64)

<0.00001

PaC02

6

4[2, 11, 17, 21]

229

108/121

- 1.54(- 1.72, - 1.36)

<0.00001

12

2[2, 17]

114

60/54

-2.00(-2.23, -1.77)

<0.00001

3

2[12, 16]

80

39/41

10.5(-16.30,37.38)

0.44

6MWD

6

5[2, 11, 17, 19, 21]

274

129/145

68.34(36.58,100.09)

<0.00001

12

3[2, 17, 19]

168

85/83

76.92(60.87,92.98)

<0.00001