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Figure 4 | Journal of Cardiothoracic Surgery

Figure 4

From: VEGF attenuates development from cardiac hypertrophy to heart failure after aortic stenosis through mitochondrial mediated apoptosis and cardiomyocyte proliferation

Figure 4

VEGF injection maintains mitochondrial fission and fusion balance and protects mitochondrial regulated apoptosis two weeks after viral injection. A, Representative EM for sham, TAC, EGFP and VEGF mice heart B, Graphs summarize the mitochondria per area and average mitochondrial size C, D, E, Representative Western blots and the results of quantitative analysis for OPA1, Bax and BcL-xL protein expression. *P < 0.05, TAC vs. Sham; †P < 0.05, VEGF vs. TAC.

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