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Table 1 Experimental results

From: Transauricular embolization of the rabbit coronary artery for experimental myocardial infarction: comparison of a minimally invasive closed-chest model with open-chest surgery

Table 1. Closed-chest transauricular coronary embolization Open-chest
surgical coronary
suture ligation
 
NZW rabbits n = 21 n = 17 P
Weight (kg) at baseline 3.15 ± 0.25 3.13 ± 0.23 0.80
Weight (kg) at 4 weeks 3.30 ± 0.3 3.27 ± 0.28 0.75
Mortality (%) 9/21 (42.9%) 5/17 (29.4%) 0.20
ECG outcomes    P
Abnormal ECG 15-20 min Immediately n/a
ST elevation (mm) 2.01 ± 0.84 1.90 ± 0.71 0.68
Blood biochemistry    P
Troponin (ng/ml) baseline 0.06 ± 0.06 0.05 ± 0.09 0.70
Troponin (ng/ml) (24 h) 47.6 ± 64.6 44.5 ± 57.7 0.88
AST baseline(U/L) 36.8 ± 21.4 33.2 ± 20.4 0.60
AST (U/L)* 110.0 ± 87.3 105.8 ± 87.6 0.88
LDH baseline(U/L) 169.4 ± 112.2 176.2 ± 101.8 0.85
LDH(U/L)* 967.4 ± 976.9 913.3 ± 820.8 0.85
CPK baseline (U/L) 1,072.0 ± 367.7 1,007.8 ± 287.2 0.55
CPK (U/L)* 6,725.8 ± 4,642.1 6,386.3 ± 3,921.4 0.81
CK -(MB) baseline (ng/ml) 0.87 ± 0.42 0.82 ± 0.33 0.68
CK -(MB) (ng/ml)* 2.88 ± 1.68 2.78 ± 1.37 0.84
Post-infarct outcomes    P
Abnormal Q waves All surviving animals All surviving animals n/a
Infarct size, cm (range) 0.92 ± 0.54 (0.3-2.0) 0.86 ± 0.35(0.5-1.7) 0.68
Baseline LVEDP (mmHg) 6.7 ± 1.8 6.2 ± 1.7 0.39
4-week LVEDP (mmHg) 12.9 ± 2.3 12.7 ± 2.0 0.78
  1. Continuous variables are presented as mean ± SD.
  2. *Maximum recorded values of serum enzymes are presented.