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Table 3 Predictors of OS according to multivariate analysis

From: Prognostic significance of postoperative serum carcinoembryonic antigen levels in patients with completely resected pathological-stage I non-small cell lung cancer

Risk factors

HR

95% CI

p valuea

Age

   

  ≤70 y

1

Reference

 

  >70 y

2.29

0.87–6.72

0.095

ECOG PS

   

  0

1

Reference

 

  1

1.33

0.47–3.53

0.59

Tumor diameter

   

  ≤30 mm

1

Reference

 

  >30 mm

3.47

1.35–8.98

0.010

VPI

   

  Absent

1

Reference

 

  Present

3.18

1.11–8.84

0.032

ALI

   

  Absent

1

Reference

 

  Present

1.06

0.38–3.15

0.91

Differentiation

   

  Well

1

Reference

 

  Moderate/Poor

1.14

0.42–3.01

0.80

Serum CEA

   

  NN group

1

Reference

 

  HN group

2.52

0.72–8.11

0.14

  HH group

7.69

2.46–23.7

< 0.001

  1. OS, Overall survival; HR, Hazard ratio; CI, Confidence interval; ECOG PS, European cooperative oncology group performance status; VPI, Visceral pleural invasion; ALI, Angiolymphatic invasion; CEA, Carcinoembryonic antigen.
  2. a the log-rank test.