Table 1 Clinicopathological factors and ERCC1 protein expression
Characteristics | No. of cases (%) (n = 115) | ERCC1 (+) (%) | ERCC1 (−) (%) | p-Value |
|---|---|---|---|---|
Age | ||||
≤65 years | 69 (60.0%) | 42 (60.9%) | 27 (39.1%) | 0.814 |
>65 years | 46 (40.0%) | 29 (63.0%) | 17 (37.0%) | |
Gender | ||||
Female | 34 (29.6%) | 17 (50.0%) | 17 (50.0%) | 0.093 |
Male | 81 (70.4%) | 54 (66.7%) | 27 (33.3%) | |
Smoking | ||||
Ever | 74 (64.3%) | 44 (59.5%) | 30 (40.5%) | 0.499 |
Never | 41 (35.7%) | 27 (65.9%) | 14 (34.1%) | |
Histology type | ||||
Adenocarcinoma | 78 (67.8%) | 52 (66.7%) | 26 (33.3%) | 0.114 |
Others | 37 (32.2%) | 19 (51.4%) | 18 (48.6%) | |
Pathological-stage | ||||
IIIA | 105 (91.3%) | 67 (63.8%) | 38 (36.2%) | 0.178 |
IIIB | 10 (8.7%) | 4 (40.0%) | 6 (60.0%) | |
T factor | ||||
T1、T2 | 83 (72.2%) | 48 (57.8%) | 35 (42.2%) | 0.165 |
T3、T4 | 32 (27.8%) | 23 (71.9%) | 9 (28.1%) | |
Operative procedure | ||||
Pneumonectomy | 25 (21.7%) | 15 (60.0%) | 10 (40.0%) | 0.840 |
Lobectomy | 90 (78.3%) | 56 (62.2%) | 34 (37.8%) | |
Number of involved lymph nodes (N1+N2) | ||||
≤5 | 59 (51.3%) | 32 (54.2%) | 27 (45.8%) | 0.089 |
>5 | 56 (48.7%) | 39 (69.6%) | 17 (30.4%) |