| |
Group
|
Before induction
|
After induction
|
Start of operation
|
Sternotomy
|
End of operation
|
|---|
|
SBP (mm Hg)
|
Control
|
136 ± 18
|
88 ± 12
|
115 ± 19
|
128 ± 15
|
115 ± 19
|
|
Landiolol
|
139 ± 24
|
93 ± 13
|
120 ± 19
|
137 ± 18*
|
118 ± 19
|
|
DBP (mm Hg)
|
Control
|
69 ± 16
|
44 ± 7
|
56 ± 11
|
63 ± 12
|
54 ± 9
|
|
Landiolol
|
72 ± 17
|
46 ± 10
|
58 ± 14
|
65 ± 15
|
56 ± 11
|
|
HR (beats/min)
|
Control
|
68 ± 12
|
54 ± 10
|
59 ± 11
|
65 ± 8
|
76 ± 9
|
| |
Landiolol
|
70 ± 12
|
58 ± 13
|
63 ± 11*
|
71 ± 12*
|
75 ± 15
|
- Values are shown as the mean ± SD. *P<0.05 vs. control (unpaired t-test). SBP: systolic blood pressure, DBP: diastolic blood pressure, HR: heart rate.
- Repeated measures ANOVA showed significant differences between the groups for SBP (p=0.03) and HR (p=0.02). SBP was significantly higher in the landiolol group at the start of the operation. SBP and HR were significantly higher in the landiolol group at sternotomy. DBP was similar in both groups.
