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Table 3 Univariate and multivariate analysis of early (≤30 days) mortality

From: Impact of prosthesis-patient mismatch on early and late mortality after aortic valve replacement

Variable Univariate analysis Multivariate analysis
P OR (95% CI) P OR (95% CI)
Age, y <0.001 1.04 (1.02-1.06) <0.001 1.04 (1.02-1.07)
Sex (female) 0.058 1.42 (0.99-2.04)   
Severely impaired LV function (EF <30%) 0.006 2.61 (1.32-5.14) 0.026 2.24 (1.10-4.56)
Hypertension 0.669 1.08 (0.75-1.56)   
Diabetes Mellitus 0.351 1.24 (0.79-1.94)   
Endocarditis 0.006 2.38 (1.28-4.44) 0.006 2.85 (1.36-5.96)
Body mass index (BMI), kg/m2 0.165 0.97 (0.93-1.01)   
Peripheral vascular disease (PVD) 0.052 1.65 (0.99-2.73)   
Renal dysfunction <0.001 2.68 (1.54-4.64) 0.032 1.90 (1.06-3.40)
Chronic obstructive pulmonary disease (COPD) 0.005 1.78 (1.19-2.68) 0.029 1.61 (1.05-2.46)
Cerebrovascular accident (CVA) 0.013 2.20 (1.18-4.08) 0.110 1.71 (0.89-3.29)
Mechanical prosthetic valve 0.418 0.86 (0.60-1.24)   
Concomitant coronary artery bypass grafting (CABG) 0.004 1.71 (1.19-2.46) 0.872 0.96 (0.62-1.51)
Cardiopulmonary bypass (CPB) time, min <0.001 1.02 (1.01-1.02) <0.001 1.01 (1.01-1.02)
Aortic cross-clamp time, min <0.001 1.02 (1.01-1.02) 0.691 1.00 (0.99-1.01)
Prosthesis-patient mismatch (PPM) (cut-off ≤ 0.85 cm2/m2) 0.014 1.80 (1.13-2.88) 0.120 1.50 (0.90-2.48)
Previous cardiac surgery <0.001 2.96 (1.90-4.59) 0.072 1.62 (0.96-2.75)
  1. CI = confidence interval; EF = ejection fraction; OR = Odds ratio; LV = left ventricular.