From: Impact of prosthesis-patient mismatch on early and late mortality after aortic valve replacement
Variable | Univariate analysis | Multivariate analysis | |||
---|---|---|---|---|---|
P | OR (95% CI) | P | OR (95% CI) | ||
Age, y | <0.001 | 1.04 (1.02-1.06) | <0.001 | 1.04 (1.02-1.07) | |
Sex (female) | 0.058 | 1.42 (0.99-2.04) | |||
Severely impaired LV function | (EF <30%) | 0.006 | 2.61 (1.32-5.14) | 0.026 | 2.24 (1.10-4.56) |
Hypertension | 0.669 | 1.08 (0.75-1.56) | |||
Diabetes Mellitus | 0.351 | 1.24 (0.79-1.94) | |||
Endocarditis | 0.006 | 2.38 (1.28-4.44) | 0.006 | 2.85 (1.36-5.96) | |
Body mass index (BMI), kg/m2 | 0.165 | 0.97 (0.93-1.01) | |||
Peripheral vascular disease (PVD) | 0.052 | 1.65 (0.99-2.73) | |||
Renal dysfunction | <0.001 | 2.68 (1.54-4.64) | 0.032 | 1.90 (1.06-3.40) | |
Chronic obstructive pulmonary disease (COPD) | 0.005 | 1.78 (1.19-2.68) | 0.029 | 1.61 (1.05-2.46) | |
Cerebrovascular accident (CVA) | 0.013 | 2.20 (1.18-4.08) | 0.110 | 1.71 (0.89-3.29) | |
Mechanical prosthetic valve | 0.418 | 0.86 (0.60-1.24) | |||
Concomitant coronary artery bypass grafting (CABG) | 0.004 | 1.71 (1.19-2.46) | 0.872 | 0.96 (0.62-1.51) | |
Cardiopulmonary bypass (CPB) time, min | <0.001 | 1.02 (1.01-1.02) | <0.001 | 1.01 (1.01-1.02) | |
Aortic cross-clamp time, min | <0.001 | 1.02 (1.01-1.02) | 0.691 | 1.00 (0.99-1.01) | |
Prosthesis-patient mismatch (PPM) (cut-off ≤ 0.85 cm2/m2) | 0.014 | 1.80 (1.13-2.88) | 0.120 | 1.50 (0.90-2.48) | |
Previous cardiac surgery | <0.001 | 2.96 (1.90-4.59) | 0.072 | 1.62 (0.96-2.75) |