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Medium-term results after implant of a new generation stentless aortic prosthesis: hemodynamic performance of medtronic 3F® stentless equine pericardial aortic valve

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Aim of this study was to evaluate the clinical and hemodynamic results at 5 years of Medtronic 3F® stentless equine pericardial aortic valve.


Between March 2007 and December 2012 a total of 120 consecutive patients affected by aortic valve disease received a 3F valve at our unit. The size ranged between 21 and 29, with prevalence of 23 and 25 implants .Mean age at operation was 75,6±8,0 years, 54% were males, the mean logistic EuroScore was 8,7±5,2 and 47% received concomitant procedures. For isolated replacements the mean ECC time was 90’±10’, Cross Clamp time 72’±8’.In 12 pts the aortic prosthesis was included in a Dacron tube straight graft for a Bentall operation.


Early mortality in isolated AVR was 2,1% and 3,1% in the entire group. There have been 6 late all-causes deaths (5,6%) ,with a survival of 90% at 5 yrs. 91% of patients are in NYHA class I or II. Actuarial freedom from reoperation for structural deterioration is 100% at 5 years. Freedom from endocarditis and thromboembolic events was 96% and 99% respectively. The 72 patients evaluated under exercise at 75w protocol showed a moderate increase in the MPG (from 7,8±3,3mmHg to 11,6±4.0mmHg) for the entire series at five years follow up.


The 3F valve shows excellent hemodynamics, durability and freedom from structural deterioration at 5 yrs follow-up. Freedom from endocarditis and thromboembolic events looks satisfactory. Longer follow-up times are needed for a better evaluation of this interesting new generation of user friendly aortic valve substitute.

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Correspondence to G Stefanelli.

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  • Aortic Valve
  • Endocarditis
  • Thromboembolic Event
  • Aortic Valve Disease
  • Cross Clamp Time