Figure 4

Effect of SEA0400 in cardioplegia on systolic Ca ²⁺ in isolated cardiomyocytes. Graph of intracellular systolic Ca²⁺ measured using fluorescent Ca²⁺ sensitive dye. Points represent mean ± SEM, n = 25 (cardioplegia with SEA0400), 24 (cardioplegia without SEA0400), and 8 (no cardioplegia). All values are normalized to the time point immediately prior to ischemia (20 min). * = p < 0.05, ϕ = <0.01, # = p < 0.001 vs. cardioplegia with SEA0400.