Table 2 Metabolic characteristics of Ossabaw swine
From: Epicardial adipose excision slows the progression of porcine coronary atherosclerosis
Parameter | Obese (n = 9) | Lean (n = 9) | P value |
|---|---|---|---|
Weight at adipectomy (kg) | 77 ± 3 | N/A | N/A |
Weight at sacrifice (kg) | 91 ± 1 | 54 ± 2 | < 0.001 |
Total cholesterol (mg/dL) | 576 ± 40 | 57 ± 6 | < 0.001 |
Fasting triglycerides (mg/dL) | 108 ± 21 | 32 ± 3 | < 0.001 |
LDL (mg/dL) | 502 ± 36 | 33 ± 1 | < 0.001 |
HDL (mg/dL) | 53 ± 7 | 24 ± 2 | < 0.005 |
LDL/HDL ratio | 11 ± 2 | 1 ± 0.1 | < 0.001 |
Fasting glucose (mg/dL) | 80 ± 5 | 73 ± 6 | 0.334 |
Plasma glucose peak (mg/dL) | 820 ± 35 | 527 ± 24 | < 0.001 |
Plasma glucose AUC | 17138 ± 1004 | 9274 ± 377 | < 0.001 |
Fasting insulin (μU/ml) | 21 ± 6 | 5 ± 1 | 0.020 |
Plasma insulin peak (μU/ml) | 172 ± 19 | 33 ± 4 | < 0.001 |
Plasma insulin AUC | 4413 ± 432 | 667 ± 121 | < 0.001 |
Systolic blood pressure (mmHg) | 138 ± 2 | 110 ± 3 | <0.001 |
Diastolic blood pressure (mmHg) | 79 ± 2 | 67 ± 2 | <0.030 |