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Table 6 In-hospital events, transfusion requirements and 30-day mortality

From: Multimodal analgesia versus traditional opiate based analgesia after cardiac surgery, a randomized controlled trial

 

Multimodal (N = 77)

Morphine (N = 74)

P value

Renal complications

  

NS

Max postop creatinine (μmol/1) (mean ± SD)

117.0 ± 60.9

102.3 ± 50.4

NS

Individual maximum rise in creatinine (μmol/1)

33.0 ± 53.4

19.9 ± 48.5

NS

Dialysis (n)

1

2

NS

Cardiac complications

   

Myocardial infarction (n)

1

2

NS

Postoperative pericardial effusion (n)

1

3

NS

Readmitted to ICU for inotropic support (n)

1

1

NS

Atrial fibrillation

31

34

NS

Cerebral complications

   

Stroke(n)

0

3

0.075(NS)

TCI (n)

0

1

NS

Involuntary movements (n)

1

0

NS

GI complications

   

GI bleeding

0

1

NS

Sternal complications

   

Sternal dehiscence

1

1

NS

Sternal infection

1

2

NS

Transfusion requirements

   

RBC (units)

1.21 ± 2.03

1.17 ± 2.10

NS

FFP (units)

0.31 ± 0.90

0.26 ± 0.84

NS

PC (units)

0.17 ± 0.48

0.10 ± 0.42

NS

Postoperative antiplatelet/anticoagulation therapy

  

NS

Aspirin

63

57

NS

Clopidogrel

2

4

NS

VKA

20

19

NS

Mortality

   

30 day mortality

1

2

NS

  1. ICU = intensive care unit, RBC = packed red blood cells, FFP = fresh frozen plasma, PC = platelet concentrates, VKA = vitamin K antagonist.