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Table 6 In-hospital events, transfusion requirements and 30-day mortality

From: Multimodal analgesia versus traditional opiate based analgesia after cardiac surgery, a randomized controlled trial

  Multimodal (N = 77) Morphine (N = 74) P value
Renal complications    NS
Max postop creatinine (μmol/1) (mean ± SD) 117.0 ± 60.9 102.3 ± 50.4 NS
Individual maximum rise in creatinine (μmol/1) 33.0 ± 53.4 19.9 ± 48.5 NS
Dialysis (n) 1 2 NS
Cardiac complications    
Myocardial infarction (n) 1 2 NS
Postoperative pericardial effusion (n) 1 3 NS
Readmitted to ICU for inotropic support (n) 1 1 NS
Atrial fibrillation 31 34 NS
Cerebral complications    
Stroke(n) 0 3 0.075(NS)
TCI (n) 0 1 NS
Involuntary movements (n) 1 0 NS
GI complications    
GI bleeding 0 1 NS
Sternal complications    
Sternal dehiscence 1 1 NS
Sternal infection 1 2 NS
Transfusion requirements    
RBC (units) 1.21 ± 2.03 1.17 ± 2.10 NS
FFP (units) 0.31 ± 0.90 0.26 ± 0.84 NS
PC (units) 0.17 ± 0.48 0.10 ± 0.42 NS
Postoperative antiplatelet/anticoagulation therapy    NS
Aspirin 63 57 NS
Clopidogrel 2 4 NS
VKA 20 19 NS
Mortality    
30 day mortality 1 2 NS
  1. ICU = intensive care unit, RBC = packed red blood cells, FFP = fresh frozen plasma, PC = platelet concentrates, VKA = vitamin K antagonist.