Sorafenib inhibits the over expression of growth factors in myocardium. Tissue levels are determined by ELISA normalized to total protein content (pg/mg). A. Sorafenib abolishes the over expression of myocardial PDGF-BB levels in banded animals (p < 0001, ***). B. Sorafenib suppresses over expression of the pro-fibrotic growth factor TGFβ1 in myocardium in banded animals (p < 0001, ***). All measurements were performed in duplicate.