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Table 2 Haemodynamic and biochemical parameters

From: Custodiol-N, the novel cardioplegic solution reduces ischemia/reperfusion injury after cardiopulmonary bypass

 

Before CBP

After CPB

 

Custodiol

Custodiol-N

Custodiol

Custodiol-N

HR (1/min)

122.5 ± 8.1

144.3 ± 8.4

130.1 ± 4.6

157.5 ± 13.1

MAP (mmHg)

89 ± 3

79 ± 5

77 ± 11

67 ± 3

CO (l/min)

2.1 ± 3.9

2.3 ± 0.4

1.9 ± 0.2

2.3 ± 0.2

CBF (ml/min)

41.3 ± 6.1

44.5 ± 3.8

26.2 ± 2.8#

58 ± 7.0*

MPO (ng/ml)

0.9 ± 0.3

1.1 ± 0.1

4.3 ± 2.2#

3.4 ± 0.4#*

Nitrite (ng/ml)

1.2 ± 0.3

1.6 ± 0.3

0.5 ± 0.2#

1.1 ± 0.3*

  1. HR: heart rate, MAP: mean arterial pressure, CO: cardiac output, CBF: coronary blood flow, MPO: plasma myeloperoxidase. All values are given as mean ± SEM. *: p < 0.05 vs. Custodiol, #: p < 0.05 vs. baseline.