From: Mid-term results of 150 TAVI comparing apical versus femoral approaches
Echocardiographic characteristics | Preoperative | Postoperative | One month | Six months | One year | Two years |
---|---|---|---|---|---|---|
Population (n) | n = 150 | n = 144 | n = 125 | n = 101 | n = 52 | n = 25 |
Mean gradient (mmHg) | 52.8 +/−11.5 | 11.8+/−4.9 | 11+/−4.6 | 11.5+/−5.2 | 11.9+/−4.4 | 11.2+/−3.8 |
p < 0.001 | p < 0.001 | |||||
Maximal gradient (mmHg) | 83.7 +/−16.1 | 21.5+/−8.1 | 22.1+/−18.8 | 21.4+/−7.7 | 20.5+/−5.6 | 19.6+/−4.3 |
p < 0.001 | p < 0.001 | |||||
Vmax (m/s) | 4.3 +/−0.8 | 2.1+/−0.4 | 1.7+/−0.5 | 1.7+/−0.6 | 1.6+/−0.5 | 1.7+/−0.5 |
p < 0.001 | p < 0.001 | |||||
Aortic area (cm2) | 0.6 +/−0.2 | 1.6+/−0.4 | 1.2+/−0.4 | 1.2+/−0.3 | 1.2+/−0.4 | 1.2+/−0.4 |
p < 0.001 | p < 0.001 | |||||
LVEF (%) | 52.8+/−12.5 | 52.4+/−12.1 | 54.6+/−10.4 | 55+/−10.7 | 54.4+/−10.9 | 52.8+/−12.5 |
p = 0.002 | p = 0.026 | p = 0.056 | ||||
Diastolic function E/E’ | 11.4+/−4.2 | 11.4+/−3.8 | 11.5+/−3.4 | 11.7+/−3.8 | 11.5+/−3.4 | 11.7+/−3.9 |
NS | ||||||
PAPS (mmHg) | 46.3+/− 12.6 | 40.8+/−12 | 41.7+/−10.7 | 41.5+/−10.5 | 40.5+/−11.2 | 38.8+/−6.4 |
p = 0.006 | p < 0.001 | p = 0.078 | p = 0.045 | |||
TAPSE (mm) | 15.2+/−3 | 13.8+/−3.2 | 15.4+/−3 | 15.1+/−2.9 | 14.8+/−3.4 | 14.2+/−3.2 |
NS | ||||||
Central aortic regurgitation | / | 4 (2.8 %) | 3 (2.4 %) | 2 (2.0 %) | 1 (1.9 %) | 0 (0 %) |
NS | ||||||
Paraprosthetic regurgitation | / | 74 (51.4 %) | 38 (30.4 %) | 14 (13.8 %) | 10 (19.2 %) | 8 (32.0 %) |
p < 0.001 | ||||||
Grade 1 | / | 35 (24.3 %) | 24 (19.2 %) | 6 (59.4 %) | 6 (11.5 %) | 6 (24.0 %) |
Grade 2 | / | 39 (27.1 %) | 13 (10.6 %) | 8 (7.9 %) | 4 (7.6 %) | 2 (8 %) |
Mitral regurgitation | 63 (42 %) | 83 (57.6 %) | 88 (70.6 %) | 72 (71.2 %) | 37 (71.1 %) | 19 (76.0 %) |
Grade 1 | 29 (19.3 %) | 12 (8.3 %) | 49 (32.2 %) | 33 (32.6 %) | 15 (19.2 %) | 8 (32.0 %) |
Grade 2 | 31 (20.7 %) | 71 (49.3 %) | 39 (31.2 %) | 39 (38.6 %) | 22 (42.3 %) | 11 (44.0 %) |
Grade 3 | 3 (2 %) | 0 (0 %) | 0 (0 %) | 0 (0 %) | 0 (0 %) | 0 (0 %) |