Univariate analysis, primary endpoint: 30-days mortality (n = 45) | |||||||
---|---|---|---|---|---|---|---|
Variable | Yes | No | O.R. | 95 %-C.I. | p-value | ||
n | % | n | % | ||||
Age > 70 y | 17 | 37.8 | 28 | 6.4 | 1.04 | (0.56 – 1.95) | 0.875 |
Female | 13 | 28.9 | 32 | 5.9 | 1.55 | (0.79 – 3.03) | 0.192 |
HT | 35 | 79.5 | 9 | 9.9 | 0.55 | (0.26 – 1.22) | 0.163 |
pulmonal. HT | 7 | 16.3 | 36 | 5.5 | 4.44 | (1.81 – 10.89) | 0.003 |
HLP | 21 | 47.7 | 23 | 13.4 | 0.27 | (0.15 – 0.51) | <0,001 |
Diab. mellitus | 18 | 40.0 | 27 | 6.1 | 1.18 | (0.64 – 2.19) | 0.632 |
BMI > 30 | 13 | 28.9 | 32 | 6.5 | 1.01 | (0.52 – 1.96) | 1.000 |
AF | 15 | 34.1 | 29 | 4.8 | 4.60 | (2.34 – 9.03) | <0,001 |
3 V–CAD | 32 | 71.1 | 13 | 10.1 | 0.54 | (0.27 – 1.05) | 0.074 |
LMS | 20 | 44.4 | 25 | 5.4 | 1.63 | (0.89 – 3.00) | 0.141 |
COPD | 9 | 20.0 | 36 | 5.8 | 2.13 | (0.99 – 4.62) | 0.080 |
PAD | 15 | 33.3 | 30 | 5.2 | 2.62 | (1.36 – 5.03) | 0.007 |
Smoker | 22 | 50.0 | 22 | 5.7 | 1.27 | (0.59 – 2.33) | 0.531 |
Crea >2 | 6 | 14.0 | 37 | 5.7 | 4.32 | (1.66 – 11.24) | 0.007 |
Renal insuff. preop. Crea <2 | 23 | 51.1 | 22 | 4.7 | 2.25 | (1.23 – 4.14) | 0.013 |
CVA | 6 | 13.6 | 38 | 6.6 | 0.79 | (0.33 – 1.91) | 0.333 |
Beta–blocker | 27 | 62.8 | 16 | 11.8 | 0.38 | (0.20 – 0.73) | 0.005 |
Statin | 22 | 51.2 | 21 | 13.6 | 0.27 | (0.14 – 0.51) | <0,001 |
Antiplatelet | 29 | 67.4 | 14 | 3.6 | 2.90 | (1.50 – 5.59) | <0,001 |
EF < 40 % | 30 | 66.7 | 15 | 3.1 | 5.36 | (2.82 – 10.21) | <0,001 |
EF 40–50 % | 8 | 17.8 | 37 | 7.0 | 0.70 | (0.32 – 1.53) | 0.466 |
EF >50 % | 7 | 15.6 | 38 | 10.4 | 0.19 | (0.08 – 0.43) | <0,001 |
Euroscore > =6 | 40 | 95.2 | 2 | 0.6 | 16.98 | (4.07 – 70.85) | <0,001 |
IABP preop. | 6 | 13.3 | 39 | 5.9 | 3.68 | (1.43 – 9.45) | 0.013 |
NYHA III + IV | 34 | 75.6 | 11 | 3.3 | 2.96 | (1.48 – 5.94) | 0.002 |
Emergent CABG | 34 | 75.6 | 11 | 2.5 | 6.43 | (3.15 – 12.76) | <0,001 |
preop. myocardial infarction | 22 | 50.0 | 22 | 4.4 | 3.26 | (1.76 – 6.06) | <0,001 |
Time between angiography and operation: | |||||||
<3d | 27 | 65.9 | 14 | 3.2 | 4.41 | (2.26 – 8.60) | <0,001 |
<24 h | 26 | 63.4 | 15 | 3.1 | 5.79 | (2.99 – 11.24) | <0,001 |
OP–time after 08.00 pm | 6 | 13.3 | 39 | 6.2 | 1.57 | (0.64 – 3.86) | 0.292 |
ICC cardioplegia | 10 | 23.8 | 32 | 6.3 | 0.89 | (0.43 – 1.86) | 0.857 |
IWC cardioplegia | 31 | 73.8 | 11 | 6.2 | 0.99 | (0.48 – 2.00) | 1.000 |
AoX < 80 min | 37 | 88.1 | 5 | 35.7 | 0.11 | (0.03 0.33) | 0.001 |
AoX > 60 min | 6 | 14.3 | 36 | 5.9 | 1.39 | (0.57 – 3.43) | 0.444 |
AoX >45 min | 13 | 31.0 | 29 | 6.3 | 0.91 | (0.46 – 1.78) | 0.866 |
CPB >180 min | 10 | 22.7 | 34 | 5.0 | 37.82 | (12.25 116.80) | <0,001 |
CPB > 120 min | 20 | 45.5 | 24 | 3.9 | 9.36 | (4.85 – 18.04) | <0,001 |
OP–time > 180 min | 33 | 73.3 | 12 | 3.9 | 2.47 | (1.25 – 4.88) | 0.008 |
Reperfusion time > 60 min | 17 | 39.5 | 26 | 4.1 | 13.40 | (6.57 – 27.34) | <0,001 |
Hemofiltration | 27 | 60.0 | IS | 3.2 | 8.54 | (4.53 – 16.10) | <0,001 |
PDI (Corotrop) | 24 | 54.5 | 20 | 2.9 | 3.71 | (2.00 – 6.90) | <0,001 |
PMI | 36 | 80.0 | 9 | 1.7 | 14.71 | (6.92 – 31.26) | <0,001 |
ICU > 3d | 29 | 69.0 | 13 | 3.3 | 3.28 | (1.67 – 6.43) | <0,001 |
ICU > 5d | 19 | 45.2 | 23 | 4.6 | 2.52 | (8.83 – 34.82) | 0.006 |
ICU > 7d | 16 | 38.1 | 26 | 4.8 | 2.59 | (1.35 – 4.97) | 0.005 |
ICU > 10d | 12 | 28.6 | 30 | 5.1 | 3.13 | (1.53 – 6.38) | 0.003 |
Hospital stay > 15 d | 10 | 22.7 | 34 | 6.3 | 1.07 | (0.51 – 2.21) | 0.851 |
Ventilation time >48 h | 23 | 62.2 | 14 | 2.6 | 11.23 | (5.54 – 22.73) | <0,001 |
IABP preop. | 27 | 60.0 | 18 | 2.9 | 15.91 | (8.25 – 30.67) | <0,001 |
ECMO | 15 | 33.3 | 30 | 4.4 | 107.83 | (29.61 – 392.72) | <0,001 |
Blood transfusion | 43 | 100.0 | 0 | 0.0 | 0.92 | (0.90 – 0.94) | 0.068 |
RBC Unit >5 | 31 | 68.9 | 14 | 2.7 | 8.48 | (4.39 – 16.39) | <0,001 |
Total blood loss >1l | 19 | 65.6 | 10 | 2.7 | 2.62 | (1.20 – 5.73) | 0.020 |
Total blood loss >2l | 12 | 41.4 | 17 | 3.0 | 6.17 | (2.82 – 13.52) | <0,001 |
Dialysis | 12 | 26.7 | 33 | 5.0 | 8.08 | (3.77 – 12.30) | <0,001 |
Inotropie support >48 h | 26 | 89.7 | 3 | 0.8 | 12.19 | (3.65 40.70) | <0,001 |
ACT > 150 sec | 10 | 41.7 | 14 | 3.1 | 4.33 | (1.85 – 10.10) | <0,001 |
Pneumonia | 10 | 22.7 | 34 | 5.1 | 12.39 | (5.19 – 29.62) | <0,001 |
Wound infection | 3 | 6.8 | 41 | 6.5 | 0.77 | (0.23 – 2.57) | 1.000 |
Operative re–exploration | 13 | 29.5 | 31 | 4.8 | 6.91 | (3.34 – 14.31) | <0,001 |