Table 1 clinical data of 7 cases of primary cardiac valve tumor
From: Surgical treatment of primary cardiac valve tumor: early and late results in eight patients
Case | Age (years) | Sex | Course (months) | Location | Measuring (cm3) | Gross Inspection | Histological Results | Surgical Procedures | Follow-up (years) |
|---|---|---|---|---|---|---|---|---|---|
1 | 21 | M | 1 | MV (anterior leaflet) | 1.5 × 0.8 × 0.5 | Light-yellow, gelatinous, relatively loose neoplasm | Myxoma | Resection of neoplasm and its original site in leaflet, cauterization and the leaflet repair | 8 Normal MV function, NYHAI |
2 | 63 | M | 25 | AV (noncoronary leaflet) | 1.5 × 1.1 × 0.8 | White elliptical neoplasm with looking like fronds surface | Papillary fibroelastoma | Complete resection of neoplasm, cauterization and CABG | 7 Mild AV regurgitation, NYHAII |
3 | 33 | M | 4 | TV (septal leaflet) | 2.0 × 1.5 × 0.7 | Light-yellow, gelatinous, relatively loose neoplasm | Myxoma | Complete resection of neoplasm and cauterization and the leaflet repair | 7.5 Normal TV function, NYHA I |
4 | 1 | M | 5 | MV (anterior leaflet) | 1.0 × 0.8 × 0.4 | Light-red elliptical neoplasm with smooth surface Fig. 1a | Rhabdomyoma desmin (++)、vimentin (++)、Ki-67 (1–2 %+)、Masson (+) Fig. 1b | Complete resection of neoplasm and cauterization | 16 Normal MV function, NYHAI |
5 | 48 | F | 3 | MV (posterior leaflet) | 4.8 × 4.0 × 2.5 | Yellow neoplasm looked like cauliflower with granular surface, destructively growth from the posterior leaflet of MV Fig. 2a | Mesenchymal sarcoma (SMA+, Vimentin+,CD34+,CD32+,MyoD1+,CD117+) Fig. 2b | Complete resection of neoplasm and mitral valve,subvalvular apparatus, replacement with 27-mm SJM mechanical valve | 6 Normal mechanical valve function, Without anticoagulation comlications INR 2.0 ~ 2.5, NYHAII |
6 | 26 | F | 6 | MV (anterior leaflet) | 1.2 × 1.0 × 0.5 | Light-yellow neoplasms resembling sea anemones with looking like fronds surface Fig. 4a | Papillary fibroelastoma Fig. 4b | Complete resection of neoplasm and leaflet, valve replacement with 27-mm Edwards bioprosthesis valve | 6.5 Normal bioprosthesis valve function, NYHAI |
7 | 10 | M | 10 | MV (anterior and posterior leaflet) | Multiple 0.2 × 0.1 × 0.1 0.4 × 0.2 × 0.1 | White neoplasms looked like granular surface Fig. 3a | Myxoma Fig. 3b | Complete resection of neoplasm and leaflet, valve replacement with 25-mm SJM mechanical valve | 4.5 Normal mechanical valve function, Without anticoagulation comlications INR 2.0 ~ 2.5, NYHAI |
8 | 62 | M | 2 | PV | 10 × 5.5 × 4.5 | Giant light-yellow neoplasms with complete capsule, destroyed the original PV Fig. 5a | Lipoma Fig. 5b | Complete resection of neoplasm and leaflet, valve replacement with 23-mm Edwards bioprosthesis valve | 1 Normal bioprosthesis valve function, NYHAII |