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Table 1 clinical data of 7 cases of primary cardiac valve tumor

From: Surgical treatment of primary cardiac valve tumor: early and late results in eight patients

Case Age (years) Sex Course (months) Location Measuring (cm3) Gross Inspection Histological Results Surgical Procedures Follow-up (years)
1 21 M 1 MV (anterior leaflet) 1.5 × 0.8 × 0.5 Light-yellow, gelatinous, relatively loose neoplasm Myxoma Resection of neoplasm and its original site in leaflet, cauterization and the leaflet repair 8 Normal MV function, NYHAI
2 63 M 25 AV (noncoronary leaflet) 1.5 × 1.1 × 0.8 White elliptical neoplasm with looking like fronds surface Papillary fibroelastoma Complete resection of neoplasm, cauterization and CABG 7 Mild AV regurgitation, NYHAII
3 33 M 4 TV (septal leaflet) 2.0 × 1.5 × 0.7 Light-yellow, gelatinous, relatively loose neoplasm Myxoma Complete resection of neoplasm and cauterization and the leaflet repair 7.5 Normal TV function, NYHA I
4 1 M 5 MV (anterior leaflet) 1.0 × 0.8 × 0.4 Light-red elliptical neoplasm with smooth surface Fig. 1a Rhabdomyoma desmin (++)、vimentin (++)、Ki-67 (1–2 %+)、Masson (+) Fig. 1b Complete resection of neoplasm and cauterization 16 Normal MV function, NYHAI
5 48 F 3 MV (posterior leaflet) 4.8 × 4.0 × 2.5 Yellow neoplasm looked like cauliflower with granular surface, destructively growth from the posterior leaflet of MV Fig. 2a Mesenchymal sarcoma (SMA+, Vimentin+,CD34+,CD32+,MyoD1+,CD117+) Fig. 2b Complete resection of neoplasm and mitral valve,subvalvular apparatus, replacement with 27-mm SJM mechanical valve 6 Normal mechanical valve function, Without anticoagulation comlications INR 2.0 ~ 2.5, NYHAII
6 26 F 6 MV (anterior leaflet) 1.2 × 1.0 × 0.5 Light-yellow neoplasms resembling sea anemones with looking like fronds surface Fig. 4a Papillary fibroelastoma Fig. 4b Complete resection of neoplasm and leaflet, valve replacement with 27-mm Edwards bioprosthesis valve 6.5 Normal bioprosthesis valve function, NYHAI
7 10 M 10 MV (anterior and posterior leaflet) Multiple 0.2 × 0.1 × 0.1 0.4 × 0.2 × 0.1 White neoplasms looked like granular surface Fig. 3a Myxoma Fig. 3b Complete resection of neoplasm and leaflet, valve replacement with 25-mm SJM mechanical valve 4.5 Normal mechanical valve function, Without anticoagulation comlications INR 2.0 ~ 2.5, NYHAI
8 62 M 2 PV 10 × 5.5 × 4.5 Giant light-yellow neoplasms with complete capsule, destroyed the original PV Fig. 5a Lipoma Fig. 5b Complete resection of neoplasm and leaflet, valve replacement with 23-mm Edwards bioprosthesis valve 1 Normal bioprosthesis valve function, NYHAII
  1. MV mitral valve, AV aortic valve, TV tricuspid valve, PV pulmonary valve