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Table 3 Linear modeling for preoperative predictors influencing survival 30 days postoperatively, postoperative atrial fibrillation and postoperative acute kidney injury

From: Impact of prophylactic administration of Levosimendan on short-term and long-term outcome in high-risk patients with severely reduced left-ventricular ejection fraction undergoing cardiac surgery – a retrospective analysis

Responses 30-days survival Postoperative AF within 24h Postoperative acute kidney injury
Parameter Coefficient Standard error p-Value Coefficient Standard error p-Value Coefficient Standard error p-Value
Prophylactic LS 0.99 0.64 0.12 0.86 0.42 0.038 -1.37 0.53 0.0094
Preoperative IABP 0.40 0.69 0.56 2.19 0.70 0.0017 -1.69 0.68 0.013
Intraoperative IABP -0.58 0.89 0.51 0.91 0.76 0.23 0.29 0.77 0.71
Postoperative IABP -2.36 1.03 0.022 0.12 1.04 0.91 1.83 1.03 0.08
Aortic cross clamp time (log) -1.04 0.84 0.21 1.40 0.57 0.014 1.45 0.64 0.024
EuroSCORE II (log) -1.12 0.35 0.0012 -0.06 0.21 0.77 0.05 0.21 0.82
BMI (log) -2.87 1.71 0.093 1.02 1.46 0.48 1.69 1.52 0.26
Preoperative admission to ICU -0.34 0.66 0.60 0.42 0.59 0.48 0.95 0.59 0.11
Preoperative TNI -0.09 0.68 0.90 -1.87 0.70 0.0074 -0.39 0.60 0.52
Preoperative CRP (log) 0.04 0.16 0.79 0.03 0.12 0.80 0.16 0.13 0.20
Preoperative white blood cell count (log) -0.20 0.82 0.81 0.43 0.61 0.48 0.62 0.70 0.38
  1. Multivariate regression analysis using generalized linear models was performed for the responses’30-days survival’, ‘postoperative new onset AF’ and ‘postoperative acute kidney injury’. LS has no significant effect on 30-days survival but contributes significantly to postoperative AF and significantly reduces postoperative acute kidney injury
  2. Abbreviations: AF: Atrial fibrillation, BMI Body-mass index, CRP C-reactive protein, IABP Intra-aortic balloon pump, ICU Intensive care unit, LS Levosimendan, TNI Troponin-I