Consumption coagulopathy in acute aortic dissection: principles of management

Table 3 Standard laboratory tests and TEG results at 5 time points according to study groups

Variable	Acute type A aortic dissection (n = 66)	Thoracic aortic aneurysm (n = 36)	p
Standard laboratory tests
White blood cells, × 10³/μl
T1**	11.45 ± 3.82	5.32 ± 0.69	<0.01
T2**	4.16 ± 2.51	7.28 ± 6.41	<0.01
T3	10.92 ± 5.59	11.54 ± 4.17	0.56
T4**	10.54 ± 4.27	13.19 ± 2.93	<0.01
T5	14.16 ± 5.56	14.59 ± 4.79	0.69
Hemoglobin, g/dL
T1	137.03 ± 17.08	136.89 ± 15.35	0.96
T2	78.34 ± 15.44	86.00 ± 22.81	0.08
T3**	89.11 ± 15.01	104.44 ± 13.82	<0.01
T4**	96.17 ± 21.52	110.67 ± 10.87	<0.01
T5**	90.76 ± 16.99	102.67 ± 9.97	<0.01
Platelet counts, × 10³/μl
T1	171.19 ± 54.27	171.22 ± 49.02	1.00
T2**	69.53 ± 33.23	102.56 ± 45.37	<0.01
T3*	96.13 ± 44.77	120.11 ± 47.82	0.01
T4**	91.59 ± 54.05	138.78 ± 41.63	<0.01
T5**	86.65 ± 46.49	120.82 ± 42.49	<0.01
TEG results
R time
T1*	6.06 ± 3.44	4.94 ± 1.16	0.02
T2	7.85 ± 1.97	8.25 ± 2.57	0.39
T3	8.03 ± 3.62	7.66 ± 2.84	0.60
T4**	8.10 ± 3.95	6.40 ± 2.33	<0.01
T5*	6.12 ± 2.42	4.97 ± 1.50	0.01
MA
T1	62.61 ± 7.30	61.96 ± 7.63	0.90
T2	47.14 ± 9.23	46.05 ± 10.92	0.61
T3	51.37 ± 11.81	48.96 ± 9.02	0.29
T4	54.80 ± 10.61	53.64 ± 5.89	0.55
T5	57.44 ± 11.67	60.12 ± 6.49	0.20
α angle
T1	65.89 ± 9.17	66.54 ± 4.85	0.69
T2	50.69 ± 11.53	51.23 ± 14.67	0.85
T3	54.96 ± 12.60	54.30 ± 12.00	0.80
T4*	54.36 ± 13.62	59.44 ± 8.17	0.02
T5**	62.49 ± 12.58	68.68 ± 3.97	<0.01

Data on the first postoperative day were unavailable for two patients with AAD
T1 = anesthesia induction; T2 = lowest nasopharyngeal temperature; T3 = protamine reversal; T4 = four hours after surgery; T5 = first postoperative day
Values are mean ± SD or median (interquartile range)
AAD acute aortic dissection, MA maximum amplitude, TEG thromboelastography
* p < 0.05 ** p < 0.01

ISSN: 1749-8090