Table 2 Association between D-dimer level and clinicopathological characteristics in patients with clinical stage I NSCLC
Variables | GroupA:D-dimer, μg/ml ≤1.0 | GroupB:D-dimer, μg/ml >1.0 | P value |
|---|---|---|---|
(n = 170) | (n = 67) | ||
n (%) | n (%) | ||
Age at operation, y | |||
< 70 | 82 (48.1%) | 31 (46.3%) | 0.785 |
≥ 70 | 88 (51.9%) | 36 (53.7%) | |
Gender | |||
Female | 68 (40.0%) | 29 (43.3%) | 0.643 |
Male | 102 (60.0%) | 38 (56.7%) | |
Smoking habit | |||
Never smoker | 70 (41.2%) | 24 (35.8%) | 0.448 |
Ever smoker | 100 (58.8%) | 43 (64.2%) | |
Serum CEA, ng/ml | |||
≤ 5 | 140 (82.3%) | 38 (56.7%) | <0.001 |
> 5 | 30 (17.7%) | 29 (43.3%) | |
Extent of pulmonary resection | |||
Segmentectomy | 24 (14.1%) | 10 (14.9%) | 0.873 |
Lobectomy or more | 146 (85.9%) | 57 (85.1%) | |
Tumor location | |||
Central | 16 (9.4%) | 8 (12.0%) | 0.561 |
Non-central | 154 (90.6%) | 59 (88.0%) | |
SUVmax of primary tumor | |||
≤ 2.3 | 123 (72.4%) | 28 (41.8%) | <0.001 |
> 2.3 | 47 (27.6%) | 39 (58.2%) | |
Tumor size, cm | |||
≤ 3 | 118 (69.4%) | 36 (53.7%) | 0.023 |
> 3 | 52 (30.6%) | 31 (46.3%) | |
Histological type | |||
AD | 139 (81.7%) | 49 (73.1%) | 0.140 |
Others | 31 (28.3%) | 18 (26.9%) | |
Grade | |||
1 | 113 (72.4%) | 43 (64.2%) | 0.738 |
2 / 3 / 4 | 57 (27.6%) | 24 (35.8%) | |
Pleural invasion | |||
Absent | 154 (90.6%) | 55 (82.0%) | 0.068 |
Present | 16 (9.4%) | 12 (18.0%) | |
Pathological stage | |||
Stage I | 154 (90.6%) | 51 (76.1%) | 0.003 |
Stage II / III | 16 (9.4%) | 16 (23.9%) | |