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Table 1 Selected case reports with review of the literature

From: Primary tracheal schwannoma a review of a rare entity: current understanding of management and followup

  Horovitz AG et al. [8] Righini CA et al. [4] Tang LF et al. [5] Xiahui GE et al. [6]
Years 1950–1983 1950–2003 1950–2005 1950–2013
Cases 13 23 34 51
Adults 11 (84.6%) 19 (82.6%) 27 (80%) 40 (78.4%)
F:M 7:5 (1 not specified) 14:4 (5 not specified) 18:13 (3 not specified) 30:20 (1 not specified)
Location in the trachea distal > proximal > middle third distal > proximal > middle third NR distal > proximal > middle third
Race White > others NR NR Asian > North American > European
Symptoms
 Common Cough, wheeze, shortness of breath and hemoptysis Upper airway obstruction with predominance of dyspnea Airway obstruction symptoms like nonspecific cough, wheezing, and dyspnea. Cough, wheezing and dyspnea
 Uncommon Fever and chest pain Hemoptysis and chest infection Hoarseness, hemoptysis, sudden severe dyspnea Hemoptysis, hoarseness and chest pain
Signs NR NR Pneumomediastinum, subcutaneous emphysema, and fever Wheeze or Stridor 15 (29%)
Investigation Fluoroscopy, Xeroradiographs and tomograms
CT of the chest
Tracheobronchoscopy
CT of the chest
MRI (1 case)
Tracheobronchoscopy
PFT
CT of the chest
MRI
Tracheobronchoscopy
PFT
CT of the chest
Tracheobronchoscopy
Delay of the diagnosis 10–15 months 10–15 months NR 17 months
Tumor size NR NR NR 1–4 cm
Treatment
 Endoscopic resection
(Laser, electronic snaring, APC, cryotherapy, endoscopic excision)
5 (38%) NR NR 19 (37%)
 Surgical resection 8 (62%) NR NR 33 (71%)
(29 primary treatment and 4 for relapse after endoscopic resection)
Recurrence
 Endoscopic resection 1 (20%) 1 (4%) 3(8.6%) 4 (21%)
 Surgery 0 (0%) 0 (0.0%) 0 (0.0%) 0 (0%)
Malignant histology NR NR 2 (5.7% 2 (3.9%)
Complication 2 NR 3 (8.6%) 3 (6%)
  ▪ Renal Failure
▪ Post-operative infection
  ▪ Renal Failure
▪ Post-operative infection
▪ Hypoxic brain damage
▪ Renal Failure
▪ Post-operative infection
▪ Hypoxic brain damage
  1. NR not recorded, CT computer tomography, MRI Magnetic Resonance Image, PFT Pulmonary Function Test, cm centimeter