Skip to main content

Advertisement

Table 1 General characteristics of patients with pneumothorax secondary to GPA

From: Risk factors and treatment of pneumothorax secondary to granulomatosis with polyangiitis: a clinical analysis of 25 cases

Clinical features Results
Male/Female (case) 18(72%)/7(28%)
Age(year) 44 ± 15.7(16~70)
Duration (weeks) 26 ± 51.0(0.83~216)
Pneumothorax type (case)  
 Pneumothorax 11(44%)
 hydropneumothorax 5 (20)
 empyemaa 8 (32%)
 Hemopneumothorax 1 (4%)
Chest Imaging(n)  
 Nodules (Multi/Single) 22(88%)
 Cavity 21(84%)
 Pulmonary hemorrhage 1 (4%)
Extrapulmonary manifestations (n)  
 Fever 11(44%)
 Skin lesions (purpura, gangrene, ulcers, etc.) 7 (28%)
 Nasal and sinus involvement 15(60%)
 Oral ulcers 5 (20%)
 Glomerulonephritis and other 13(52%)
 Nervous system (facial paralysis, mononeuropathy, etc.) 6 (24%)
 Arthralgia/arthritis 11(44%)
 Parotid swelling 2 (8%)
Laboratory tests  
 ANCA-positive(n) 13/20(65%)
 Anti-PR3(RU/ml) 176 ± 145.3(26~411)
 ESR (mm/h) 92 ± 31.6(24~145)
 CRP (mg/dl) 20 ± 27.4(2.35–90)
Pleural drainage(n) 16
Surgery(n) 7 (28%)
Spontaneous absorption(n) 4 (16%)
Death 10(40%)
  1. Note: ANCA, anti-neutrophil cytoplasmic antibodies; anti-PR3, anti-proteinase 3 antibody; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein
  2. aThese cases with empyema showed a clear pneumothorax at chest X-ray or CT scan