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Table 2 Associations between SIRT1 expressions and clinicopathological parameters in 155 patients with esophageal squamous cell carcinoma receiving esophagectomy

From: SIRT1 overexpression is an independent prognosticator for patients with esophageal squamous cell carcinoma

Parameters

SIRT1 expression

Low

Over

P value

Age

<55y/o

32

37

0.38

≧55y/o

46

40

 

Sex

Male

75

75

1.00

Female

3

2

 

Primary tumor location

U + M

40

42

0.68

L

38

35

 

T classification

T1 + T2

45

34

0.092

T3 + T4

33

43

 

N classification

N0

55

51

0.57

N1 + 2 + 3

23

26

 

7th AJCC Stage

I + II

57

55

0.82

III + IV

21

22

 

Histological grading

Grade 1 + 2

66

58

0.15

Grade 3

12

19

 

Surgical margin

Negative

75

60

0.38

Positive

9

11

 
  1. AJCC American Joint Committee on Cancer, SIRT1 Sirtuin1, p-p70S6K phosphorylated p70 ribosomal S6 protein kinase