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Table 2 Associations between SIRT1 expressions and clinicopathological parameters in 155 patients with esophageal squamous cell carcinoma receiving esophagectomy

From: SIRT1 overexpression is an independent prognosticator for patients with esophageal squamous cell carcinoma

Parameters SIRT1 expression
Low Over P value
Age <55y/o 32 37 0.38
55y/o 46 40  
Sex Male 75 75 1.00
Female 3 2  
Primary tumor location U + M 40 42 0.68
L 38 35  
T classification T1 + T2 45 34 0.092
T3 + T4 33 43  
N classification N0 55 51 0.57
N1 + 2 + 3 23 26  
7th AJCC Stage I + II 57 55 0.82
III + IV 21 22  
Histological grading Grade 1 + 2 66 58 0.15
Grade 3 12 19  
Surgical margin Negative 75 60 0.38
Positive 9 11  
  1. AJCC American Joint Committee on Cancer, SIRT1 Sirtuin1, p-p70S6K phosphorylated p70 ribosomal S6 protein kinase