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Table 1 Baseline characteristics according to randomized left atrial appendage closure

From: Adding left atrial appendage closure to open heart surgery provides protection from ischemic brain injury six years after surgery independently of atrial fibrillation history: the LAACS randomized study

Variable

Not closed (n = 86)

Closed (n = 101)

 

Age – years

69.3 ± 8.8

67.6 ± 9.6

 

Men - n (%)

75 (87.2)

84 (83.2)

 

Clinical characteristics

 Congestive heart failure - n (%)

15 (17.9)

16 (15.8)

 

 Atrial fibrillation - n (%)

12 (12.8)

18 (16.8)

 

 Diabetes - n (%)

19 (22.1)

31 (30.7)

 

 Hypertension - n (%)

60 (69.8)

75 (74.3)

 

 CHADS-VASc – unit

2.9 ± 1.4

2.9 ± 1.5

 

 Prior stroke - n (%)

15 (17.4)

11 (10.9)

 

 Chronic kidney diseasea - n (%)

14 (16.3)

15 (14.9)

 

Medicine

 ASA - n (%)

69 (80.2)

75 (74.3)

 

 Clopidogrel - n (%)

14 (16.3)

19 (18.8)

 

 OAC

  VKA - n (%)

26 (30.2)

36 (35.6)

 

  NOAC - n (%)

2 (2.2)

2 (2.0)

 

 Beta-blocker - n (%)

47 (54.7)

61 (60.4)

 

 Verapamil - n (%)

4 (4.5)

2 (2.0)

 

 Calcium-blocker - n (%)

19 (21.3)

34 (33.7)

 

 Digoxin - n (%)

5 (5.6)

3 (3.0)

 

 Renin-angiotensin system blocker - n (%)

40 (46.5)

54 (53.5)

 

 Amiodarone - n (%)

23 (26.7)

18 (17.8)

 

 Statin - n (%)

74 (86.0)

81 (80.2)

 

Procedural characteristics

Surgery type

 AVR only - n (%)

17 (19.1)

17 (16.8)

 

 AVR with CABG - n (%)

20 (22.5)

22 (21.8)

 

 AVR with aortic surgery - n (%)

1 (1.1)

1 (1.0)

 

 AVR with MVR - n (%)

0 (0)

2 (2.0)

 

 Aortic surgery only - n (%)

1 (1.1)

0 (0)

 

 CABG only - n (%)

40 (46.5)

50 (49.5)

 

 CABG with MVR - n (%)

2 (2.3)

2 (2.0)

 

 MVR only - n (%)

4 (4.5)

7 (6.9)

 

 Tricuspid surgery only - n (%)

1 (1.2)

0 (0)

 

Perioperative atrial fibrillation - n (%)

52 (60.5)

50 (50.0)

 
  1. Abbreviations CHADS-VASc Congestive heart failure, hypertension, age [≥75 years], diabetes, stroke – peripheral vascular disease, age [≥65 years], sex-category, OAC Oral anticoagulation, VKA Vitamin K-antagonist, NOAC Novel oral anticoagulation, IQR: interquartile range
  2. aeGFR< 30 ml/min